+1-617-394-8820 contact@baybiosciences.com

Sneezing Overview

Sneezing is a protective reflex which usually happens suddenly and without any warning. A sneeze is a powerful, involuntary expulsion of air. It’s the body’s way of removing irritants from the nose or throat. Sneezing is also known as sternutation is a routine function in humans and many animals. While sneezing as a symptom can be quite annoying, it’s not usually the result of any serious health problem.

People sneeze to remove from the nasal cavities mucus containing foreign particles or irritants. A sneeze (or sternutation) expels air forcibly from the mouth and nose in an explosive, spasmodic involuntary action caused mainly from irritation of the nasal mucous membrane. During a sneeze, the soft palate and palatine uvula are lowered while the back of the tongue rises to partially close the passage to the mouth so that air expelled by the lungs can exist the nose. Because the mouth closes only partially, much of this air is also expelled through it; the power and amount of air pushed through the nose varies. There is actually a “sneezing center” in the brain that causes the nose to react to stimulants. The sudden air can be expelled by the nose at high speeds of 1 kPa through the upper airways.

What Triggers a Sneeze

Many things can trigger a sneeze, sneezing can be triggered through cold, sudden exposure to bright light, a particularly full stomach and physical stimulants of the trigeminal nerve, as a result of central nervous system pathologies such as epilepsy, posterior inferior cerebellar artery syndrome or as a symptom of psychogenic pathologies. Further more, sneezing can also be triggered by a drop in temperature or a cold breeze, allergies, exposure to chemicals, a full stomach, having or thinking about sex and orgasm, touching something, being exposed to an electric current. Sneezing is the semi-autonomous , convulsive expulsion of air through the lungs and the mouth, usually caused by foreign particles irritating the nasal mucosa.

Sneezing is a coordinated protective respiratory reflex which occurs due to stimulation of the upper respiratory tract, particularly the nasal cavity. The sneeze reflex frequently accompanies rhinitis of allergic or nonallergic origin. Sneezing can also arise due to bright light or sun (ACHOO syndrome), physical stimulants of the trigeminal nerve, psychogenic or central nervous system pathologies and even due to a full stomach (snatiation reflex) or a sexual ideation.

Sneezing does not Occur during sleep

Sneezing does not occur at any time, for examples when you are in a deep rapid-eye-movement (REM) sleep, you can’t sneeze because your body has gone into a state of atonia when the motor neurons cannot be stimulated and the brain does not receive signals of reflexes. But if you wake up in the middle of (REM) sleep you can start sneezing. The sneeze reflex involves various nerves in the brainstem that control muscles in the throat and lungs.

Signs and Symptoms of Sneezing

Depending upon the reason for the sneezing, other symptoms can also occur, including:

  • Burning, itchy, or watery eyes
  • Nasal congestion or runny nose
  • Sore throat
  • Cough
  • Fever
  • Chills

Causes of Sneezing

Sneezing can be triggered by a variety of things, including:

  • Allergens
  • Anesthetics
  • Viruses, such as the common cold or flu
  • Nasal irritants
  • Inhalation of corticosteroids through a nasal spray
  • Drug withdrawal

Other Causes of Sneezing

  • Air Pollutants
  • Cold Air
  • Drug Withdrawal
  • Dust
  • Exposure to Bright Light
  • Medications
  • Spicy Foods 
  • Strong Emotions
  • Viral Infection
  • Capsaicin

Capsaicin, the active chemical component of chili peppers, is a prime cause of sneezing for both animals and humans. Inhaling it produces a sensation of burning in any tissue with which it comes into contact.

Part of your nose’s job is to clean the air we breathe, making sure it’s free of dirt and bacteria. In most cases, our nose traps this dirt and bacteria in mucus. Your stomach then digests the mucus, which neutralizes any potentially harmful invaders. Sometimes, however, dirt and debris can enter your nose and irritate the sensitive mucous membranes inside your nose and throat. When these membranes become irritated, it causes you to sneeze.

A widely used anesthetic called propofol (Diprivan) that anesthesiologists use can cause multiple sneezing, according to a study in a CMAJ. Some patients react so strongly to this that the operating table shakes, causing the surgeon problems. One involuntarily sneezing patient was even stabbed in the eye by the surgeon’s scalpel. Yet the psychoactive substances known as opioids such as Fentanyl have been found to prevent sneezing during surgery, especially on the eyes. 

BayBiosciences.com is a global leader in providing researchers with high quality, clinical grade, fully characterized human tissue samples, bio-specimens and human bio-fluid collections from cancer (tumor tissue, cancer-serum, cancer-plasma, cancer-PBMC) and from most other diseases.

Bay Biosciences maintains and manages it’s own bio-repository, human tissue bank (biobank) consisting of thousands of diseased and normal human tissue samples (specimens) in all formats. Our biobank procures and stores fully consented, deidentified and institutional review boards (IRB) approved human tissue samples and human specimens.

All our human tissue sample collections, human specimens and human bio-fluids are provided with detailed associated patient clinical data. Patients clinical data include information relating to their past and current disease, treatment history, lifestyle choices, biomarkers and genetic information. Patient data is extremely valuable for researchers and is used to help identify new effective treatments (drug discovery & development) in oncology, other therapeutic areas and other diseases, and demonstrate their impact, monitor the safety of medicines, testing & diagnostics, and generate new knowledge about the causes of disease and illness. 

Bay Biosciences banks wide variety of human tissue samples and biological samples including cryogenically preserved -80°C, fresh, frozen samples, FFPE’s, tissue slides, with matching human bio-fluids such as whole blood and blood derived products such as serum, plasma, PBMCs.

Bay Biosciences is a global leader in collecting and providing human tissue samples according to the researchers specified requirements and customized, tailor made collection protocols. Please contact us anytime to discuss your special research projects and customized human tissue sample requirements.

Bay Biosciences provides human tissue samples (human specimens) from diseased and normal healthy donors; including peripheral whole-blood, amniotic fluid, bronchoalveolar lavage fluid (BAL), sputum, pleural effusion, cerebrospinal fluid (CSF), serum (sera), plasma, peripheral blood mononuclear cells (PBMC’s), saliva, buffy coat, urine, stool samples, kidney stones, renal calculi, nephrolithiasis, urolithiasis and other bodily fluids from most diseases including cancer. In addition to the above human bio-specimens we can procure All our human tissue samples are procured through IRB approved clinical protocols and procedures. 

 In addition to the standard processing protocols Bay Biosciences can also provide human plasma, serum, PBMC bio-fluid samples using custom processing protocols, donor specific collections in higher volumes and specified sample aliquoting. Bay Biosciences also provides human samples from normal healthy donors, volunteers, for controls and clinical research, contact us Now.