Bay Biosciences provides high quality, clinical grade fresh frozen Biliary Tract Cancer (BTC) Adenocarcinoma tumor tissue specimens, with matched cryogenically preserved sera (serum), plasma and peripheral blood mononuclear cells (PBMC) biofluid samples.  

Moreover, The serum and plasma samples are processed from unique patients whole blood following customized protocols, from unique biliary tract cancer patients to a valued pharmaceutical customer for research, diagnostics, development and drug discovery.

Biliary Tract Cancer

Biliary tract cancer, also known as cholangiocarcinoma, is a rare adenocarcinoma that occurs in a bile duct; consequently, it often causes jaundice, pruritus, and weight loss. Additionally, the lesion may be papillary or flat and ulcerated. Furthermore, biliary tract cancers (BTCs) are rare and have a poor prognosis; thus, the tumor is often un-resectable at diagnosis.

The bile ducts, on the other hand, are a series of thin tubes that go from the liver to the small intestine. Their major job is to move a fluid called bile from the liver and gallbladder into the small intestine, where it, in turn, helps digest the fats in food.

Most bile duct cancers, or cholangiocarcinomas, are adenocarcinomas, which are cancers that start in glandular cells. Specifically, bile duct adenocarcinomas start in the mucous gland cells that line the inside of the ducts.

Types of Bile Duct Cancers

Cancer can start in any part of the bile duct system; consequently, depending on where the cancers are, they are grouped mainly into the following three types:

  • 1. Intrahepatic bile duct cancers
  • 2. Perihilar, also known as hilar bile duct cancers
  • 3. Distal bile duct cancers

Intrahepatic Bile Duct Cancers

These cancers start in the smaller bile duct branches inside the liver. However, sometimes they’re confused with cancers that start in the liver cells, which are called hepatocellular carcinomas; indeed, these are often treated the same way.

Perihilar or Hilar Bile Duct Cancers

In addition, perihilar cancers start at the hilum, where the left and right hepatic ducts have joined and are just leaving the liver. Consequently, these are also called Klatskin tumors. Furthermore, perihilar cancers are grouped with distal bile duct cancers as extrahepatic bile duct cancers.

Distal Bile Duct Cancers

On the other hand, distal cancers are found further down the bile duct, closer to the small intestine. Similar to perihilar cancers, these are extrahepatic bile duct cancers because they start outside of the liver.

Moreover, detailed clinical data, including genetic test info, KRAS, EGFR, IDH, FGFR, and BAP1, as well as biomarker information including LFT, alkaline phosphatase, AST, ALT, and GGT test results, are provided.

In addition, biopsy and pathology annotations, along with the patient’s history associated with the Biliary Tract cancer samples, are provided to a valued customer for drug discovery, development, and research. Furthermore, the sera (serum) and plasma samples were processed using customized protocols provided by the researcher.

Ultimately, Bay Biosciences specializes in providing researchers with customized human samples and bio-specimens collections.

Biospecimens

biospecimens

Bay Biosciences is a global leader in providing researchers with high quality, clinical grade, fully characterized human tissue samples, bio-specimens, and human bio-fluid collections.

Moreover, human biospecimens are available including tumor tissue, serum, plasma and PBMC samples from most other therapeutic areas.

Furthermore, Bay Biosciences maintains and manages its own biorepository, the human tissue bank (biobank) consisting of thousands of diseased samples (specimens) and likewise normal healthy donors for controls. Additionally, available in all formats and types.

In fact, our biobank procures and stores fully consented, de-identified and institutional review boards (IRB) approved human tissue samples, human biofluids such as serum samples, plasma samples from various diseases and matched controls.

Also, all our human tissue collections, human biospecimens and human biofluids are provided with detailed, samples associated patient’s clinical data.

In fact, this critical patient’s clinical data includes information relating to their past and current disease, treatment history, lifestyle choices, biomarkers, and genetic information.

Additionally, researchers find the patient’s data associated with the human biospecimens extremely valuable and use it to help identify new effective treatments (drug discovery & development) in oncology, as well as in other therapeutic areas and diseases.

Bay Biosciences banks wide variety of human tissue samples and human biological samples, including fresh frozen human biospecimens cryogenically preserved at – 80°C.

For example fresh frozen tissue samples, tumor tissue samples, formalin-fixed paraffin-embedded (FFPE), tissue slides, with matching human bio-fluids, whole blood and blood-derived products such as human serum, human plasma and human PBMCs.

Bay Biosciences is a global leader in collecting and providing human tissue samples according to the specified requirements and customized, tailor-made collection protocols.

Please contact us anytime to discuss your special research projects and customized human tissue sample requirements.

Types of Biospecimens

Bay Biosciences provides human tissue samples (human specimens) and human biofluids from diseased and normal healthy donors which includes:

Moreover, we can also procure most human biospecimens and human biofluids, special collections and requests for human samples that are difficult to find. All our human tissue samples and human biofluids are procured through IRB-approved clinical protocols and procedures.

In addition to the standard processing protocols, Bay Biosciences can also provide human biofluids such as  human plasma, human serum, and human PBMCs bio-fluid samples using custom processing protocols; you buy donor-specific collections in higher volumes and specified sample aliquots from us.

Bay Biosciences also provides human biospecimens from normal healthy donors; volunteers, for controls and clinical research, Contact us Now.