Bay Biosciences provides fresh frozen serum and plasma with matching saliva samples from mild Traumatic Brain Injury (mTBI) patients taken at multiple intervals of time, with detailed associated clinical information. Samples processed and handled, under custom protocols provided by the researcher.

Traumatic Brain Injury (TBI) Overview

A traumatic brain injury (TBI) is an injury to the brain or skull caused by an external force. Consequently, brain injuries are often permanent and disabling, unlike other injuries, such as broken legs or cuts that can heal.

In addition, TBI occurs from a sudden blow or jolt to the head which often occurs during a traumatic event. Such as sports injuries, gunshot wounds, physical aggression, an accident, blast, or fall.

In fact, the CDC defines a TBI as “a disruption in the normal function of the brain. This can be caused by a bump, blow, or jolt to the head, or penetrating head injury.”

Hence, severity of symptoms will depend on which part of the brain is affected. Furthermore, this can be in a specific location or over a widespread area, and the extent of the damage.

Therefore, in mild cases, temporary confusion and headache may occur. Moreover, serious TBI can result in unconsciousness, amnesia, disability, coma, and death or long-term impairment.

The CDC estimate that, in 2013, TBI contributed to the deaths of some 50,000 people. In fact, in 2012, 329,290 people aged under 19 years sought emergency treatment for a TBI. Consequently, resulting from a sporting or recreational activity.

How Serious is Traumatic Brain Injury (TBI)

A TBI can be mild, moderate, or severe. These terms refer to the nature of the injury itself. For example, the factors that determine severity are whether or how long you lost consciousness (got knocked out), if you remember the event, and if there is damage to the brain. TBI-related symptoms vary from person to person, so they may not be the same, even for people with similar severity of TBI.

However, if you weren’t knocked out at all or if you were unconscious for less than 30 minutes, your TBI was most likely minor or mild. This is the most common type of TBI, and most symptoms related to a mild TBI will resolve. A mild TBI (or mTBI) may also be called a concussion.

If you were knocked out for more than 30 minutes but less than 24 hours, your TBI was most likely moderate. Being unconscious for more than 24 hours is usually a severe TBI.

Types of Traumatic Brain Injury (TBI)

Traumatic brain injuries may be penetrating or non-penetrating (blunt):

  • Penetrating TBI: A penetrating TBI is when something pierces your skull, enters your brain tissue and damages a part of your brain. Healthcare providers may call these open TBIs. Penetrating TBIs may happen if you’re hit in the head by a sharp object, like shrapnel, a bullet or a knife.
  • Blunt TBI: A non-penetrating TBI is when something hits your head hard enough that your brain bounces or twists around inside your skull. Providers may use the terms closed head TBI or blunt TBI for this kind of TBI. Non-penetrating TBIs may happen if you’re in a vehicle accident, take a fall, are hit in the head, injured in an explosion or are injured while playing sports.

Furthermore, healthcare providers classify traumatic brain injuries as being mild, moderate and severe. However, they may use the term concussion when talking about mild TBI. They typically group moderate and severe TBI together.

  • Mild TBI: More than 75% of all TBIs are mild. But even mild TBIs may cause significant and long-term issues. People with a mild traumatic brain injury may have trouble returning to their daily routines, including being able to work.
  • Moderate and severe TBI: Most people with a moderate or severe traumatic brain injury can develop significant and long-term health issues.

Symptoms of Traumatic Brain Injury (TBI)

If you have a traumatic brain injury, it means you were hit in the head hard enough to make your brain bounce around or twist inside your skull. When that happens, you can damage your brain and injure blood vessels in your brain. A TBI creates chemical changes in your brain so your brain cells don’t function as they should.

Traumatic brain injury symptoms vary depending on whether a TBI is mild or moderate and/or severe. But all TBIs may cause symptoms, including physical issues, trouble thinking or remembering, and social or emotional issues.

 

Biospecimens

Bay Biosciences is, indeed a global leader in providing researchers with high quality, clinical grade, fully characterized human tissue samples, bio-specimens, and human bio-fluid collections.

Specifically, aamples available include cancer (tumor) tissue, cancer serum, cancer plasma, cancer, peripheral blood mononuclear cells (PBMC). and human tissue samples from most other therapeutic areas and diseases.

Moreover, Bay Biosciences maintains and manages its own biorepository, the human tissue bank (biobank) consisting of thousands of diseased samples (specimens) and from normal healthy donors available in all formats and types.

In fact, our biobank procures and stores fully consented, de-identified and institutional review boards (IRB) approved human tissue samples and matched controls.

Additionally, all our human tissue collections, human specimens and human bio-fluids are provided with detailed, samples associated patient’s clinical data.

In particular, critical patient’s clinical data includes information relating to their past and current disease, treatment history, lifestyle choices, biomarkers, and genetic information.

Moreover, patient’s data is extremely valuable for researchers and is used to help identify new effective treatments (drug discovery & development) in oncology, and other therapeutic areas and diseases.

Specifically, Bay Biosciences banks wide variety of human tissue samples and biological samples, including cryogenically preserved at – 80°C.

For example fresh frozen tissue samples, tumor tissue samples, formalin-fixed paraffin-embedded (FFPE), tissue slides, with matching human bio-fluids, whole blood and blood-derived products such as serum, plasma and PBMC.

Furthermore, Bay Biosciences is a global leader in collecting and providing human tissue samples according to the specified requirements and customized, tailor-made collection protocols.

Therefore, please contact us anytime to discuss your special research projects and customized human tissue sample requirements.

Types of Biospecimens

Bay Biosciences provides human tissue samples (human specimens) from diseased and normal healthy donors which includes:

Customized Collections

Moreover, we can also procure most human bio-specimens, furthermore; we offer special collections and requests for human samples that are difficult to find. All our human tissue samples are procured through IRB-approved clinical protocols and procedures.

In addition to the standard processing protocols, Bay Biosciences can also provide human plasma, serum, and PBMC bio-fluid samples using custom processing protocols. Additionally you buy donor-specific collections in higher volumes and specified sample aliquots from us.

Furthermore, Bay Biosciences also provides human samples from normal healthy donors; volunteers, for controls and clinical research, contact us Now.

 

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