Alveoli Overview

Alveoli are tiny air sacs at the end of the bronchioles (tiny branches of air tubes in the lungs). Furthermore, the alveoli are where the lungs and the blood, exchange oxygen and carbon dioxide during the process of breathing in and breathing out.

Specifically, oxygen breathed in from the air passes through the alveoli and into the blood. And subsequently travels to the tissues throughout the body. Meanwhile, carbon dioxide travels in the blood from the body’s tissues and passes through the alveoli to be breathed out.

In addition, alveoli are an important part of the respiratory system. Whose function it is to exchange oxygen and carbon dioxide molecules to and from the bloodstream. Notably, these tiny, balloon-shaped air sacs sit at the very end of the respiratory tree and are arranged in clusters throughout the lungs.

Moreover, alveoli are tiny balloon-shaped structures and are the smallest passageway in the respiratory system. Consequentl, the alveoli are very thin. Allowing the relatively easy passage of oxygen and carbon dioxide (CO2) between the alveoli and blood vessels known as capillaries.

The alveoli are made up of two different types of cells that perform different functions:

  • First, Type I pneumocytes are the cells that are responsible for the exchange of oxygen and carbon dioxide.
  • In addition, Type II pneumocytes perform two important functions. They are responsible for repairing damage to the alveolar lining and also secrete surfactant.

Moreover, there are also many immune cells known as alveolar macrophages in the alveoli. In fact, macrophages are essentially the garbage trucks of the immune system. They phagocytize or “eat” debris they come across. Consequently, they are responsible for cleaning up any particles that are not caught by the cilia or mucus in the upper respiratory tract, as well as dead cells and bacteria.

Biospecimens

biospecimens

Bay Biosciences is a global leader in providing researchers with high quality, clinical grade, fully characterized human tissue samples, bio-specimens, and human bio-fluid collections.

Moreover, human biospecimens are available including tumor tissue, serum, plasma and PBMC samples from most other therapeutic areas.

Furthermore, Bay Biosciences maintains and manages its own biorepository, the human tissue bank (biobank) consisting of thousands of diseased samples (specimens) and likewise normal healthy donors for controls. Additionally, available in all formats and types.

In fact, our biobank procures and stores fully consented, de-identified and institutional review boards (IRB) approved human tissue samples, human biofluids such as serum samples, plasma samples from various diseases and matched controls.

Also, all our human tissue collections, human biospecimens and human biofluids are provided with detailed, samples associated patient’s clinical data.

In fact, this critical patient’s clinical data includes information relating to their past and current disease, treatment history, lifestyle choices, biomarkers, and genetic information.

Additionally, researchers find the patient’s data associated with the human biospecimens extremely valuable and use it to help identify new effective treatments (drug discovery & development) in oncology, as well as in other therapeutic areas and diseases.

Bay Biosciences banks wide variety of human tissue samples and human biological samples, including fresh frozen human biospecimens cryogenically preserved at – 80°C.

For example fresh frozen tissue samples, tumor tissue samples, formalin-fixed paraffin-embedded (FFPE), tissue slides, with matching human bio-fluids, whole blood and blood-derived products such as human serum, human plasma and human PBMCs.

Bay Biosciences is a global leader in collecting and providing human tissue samples according to the specified requirements and customized, tailor-made collection protocols.

Please contact us anytime to discuss your special research projects and customized human tissue sample requirements.

Types of Biospecimens

Bay Biosciences provides human tissue samples (human specimens) and human biofluids from diseased and normal healthy donors which includes:

Moreover, we can also procure most human biospecimens and human biofluids, special collections and requests for human samples that are difficult to find. All our human tissue samples and human biofluids are procured through IRB-approved clinical protocols and procedures.

In addition to the standard processing protocols, Bay Biosciences can also provide human biofluids such as  human plasma, human serum, and human PBMCs bio-fluid samples using custom processing protocols; you buy donor-specific collections in higher volumes and specified sample aliquots from us.

Bay Biosciences also provides human biospecimens from normal healthy donors; volunteers, for controls and clinical research, Contact us Now.