Bay Biosciences supplies researchers with fresh frozen serum, plasma, peripheral blood mononuclear cells (PBMC) biofluid samples and matching FFPE blocks from unique patients diagnosed with Discoid Lupus, therefore facilitating research, development, and discovery.

Discoid Lupus Erythematosus (DLE) Overview

Discoid lupus (Discoid Lupus Erythematosus) is a chronic autoimmune disease that affects the skin. Specifically, it receives its name from the coin-shaped lesions it produces. Furthermore, this condition causes a severe rash that tends to worsen when exposed to sunlight.

In addition, the rash can appear anywhere on the body; however, you’re likely to see it on the scalp, neck, hands, and feet. Consequently, severe cases can lead to permanent scarring, hyperpigmentation, and hair loss.

The disease can damage any part of the body. It is defined as chronic, meaning that symptoms occur for a long time or happen repeatedly.

The National Resource Center on Lupus estimates that, in fact, at least 1.5 million Americans have lupus.

Moreover, systemic lupus erythematosus, or SLE, is the most common form of lupus that affects joints, muscles, various tissues, and organs in the body.

Conversely, cutaneous lupus erythematosus, or CLE, refers to forms of lupus that affect the skin and cause rashes and sores.

In particular, discoid lupus is the most common type of CLE. Furthermore, it is an autoimmune disease, which means that the immune system mistakenly identifies its own tissue as foreign and mounts an attack.

Consequently, a healthy immune system fights off viruses and bacteria that can cause illness. However, with discoid lupus, the immune system attacks healthy skin, causing sores that appear as a disc-shaped rash.

Symptoms of Discoid Lupus

Discoid sores, therefore, present as a distinctive thick, scaly rash, ranging in color from red to purple.

Moreover, the rash can appear in one place or, alternatively, in a number of areas on the body. Specifically, it is most likely to appear on areas of the skin that regularly receive sunlight, such as the face, neck, and backs of the hands.

Usually, no other symptoms occur; however, some people may feel pain or an itch within the sores. Furthermore, other skin conditions can look very similar to discoid lupus, such as plaque psoriasis or eczema. Thus, it is important for people to see a doctor in order to get an accurate diagnosis.

Causes of Discoid Lupus

Like all forms of lupus, discoid lupus does not have one clear cause.

In fact, hormones, genetic factors, and environmental triggers can all play a part in the development of the disease. **For example,** examples of environmental triggers include exposure to ultraviolet light and stress.

Furthermore, groups of people who are more at risk of discoid lupus include:

  • Namely, people with a family history of lupus or other diseases of the immune system
  • In addition, women, who make up more than 90 percent of people with lupus
  • Moreover, African-Americans, who are three times more at risk for lupus than Caucasians
  • And finally, 20-to-50-year olds

Biospecimens

Bay Biosciences is, indeed a global leader in providing researchers with high quality, clinical grade, fully characterized human tissue samples, bio-specimens, and human bio-fluid collections.

Specifically, aamples available include cancer (tumor) tissue, cancer serum, cancer plasma, cancer, peripheral blood mononuclear cells (PBMC). and human tissue samples from most other therapeutic areas and diseases.

Moreover, Bay Biosciences maintains and manages its own biorepository, the human tissue bank (biobank) consisting of thousands of diseased samples (specimens) and from normal healthy donors available in all formats and types.

In fact, our biobank procures and stores fully consented, de-identified and institutional review boards (IRB) approved human tissue samples and matched controls.

Additionally, all our human tissue collections, human specimens and human bio-fluids are provided with detailed, samples associated patient’s clinical data.

In particular, critical patient’s clinical data includes information relating to their past and current disease, treatment history, lifestyle choices, biomarkers, and genetic information.

Moreover, patient’s data is extremely valuable for researchers and is used to help identify new effective treatments (drug discovery & development) in oncology, and other therapeutic areas and diseases.

Specifically, Bay Biosciences banks wide variety of human tissue samples and biological samples, including cryogenically preserved at – 80°C.

For example fresh frozen tissue samples, tumor tissue samples, formalin-fixed paraffin-embedded (FFPE), tissue slides, with matching human bio-fluids, whole blood and blood-derived products such as serum, plasma and PBMC.

Furthermore, Bay Biosciences is a global leader in collecting and providing human tissue samples according to the specified requirements and customized, tailor-made collection protocols.

Therefore, please contact us anytime to discuss your special research projects and customized human tissue sample requirements.

Types of Biospecimens

Bay Biosciences provides human tissue samples (human specimens) from diseased and normal healthy donors which includes:

Customized Collections

Moreover, we can also procure most human bio-specimens, furthermore; we offer special collections and requests for human samples that are difficult to find. All our human tissue samples are procured through IRB-approved clinical protocols and procedures.

In addition to the standard processing protocols, Bay Biosciences can also provide human plasma, serum, and PBMC bio-fluid samples using custom processing protocols. Additionally you buy donor-specific collections in higher volumes and specified sample aliquots from us.

Furthermore, Bay Biosciences also provides human samples from normal healthy donors; volunteers, for controls and clinical research, contact us Now.

 

  • 日本のお客様は、ベイバイオサイエンスジャパンBay Biosciences Japanまたはhttp://baybiosciences-jp.com/contact/までご連絡ください。