Bay Biosciences provides high quality, clinical grade bio-samples, cryogenically preserved biopsy tissue, FFPE blocks with matched sera (serum), plasma and peripheral blood mononuclear cells (PBMC) biofluid specimens from patients diagnosed with Hashimoto’s Thyroiditis disease.
The sera (serum), plasma and peripheral blood mononuclear cells (PBMC) biofluid samples are processed from patient’s peripheral whole-blood using customized collection and processing protocols. The Hashimoto’s Thyroiditis bio-specimens are collected from unique patients diagnosed with from Hashimoto’s Thyroiditis disorder and are provided to a valued pharmaceutical customer for genomics, proteomics, biomarkers, research, development and drug discovery.
Hashimoto’s Thyroiditis Disease
Hashimoto’s disease is a condition in which the immune system attacks the thyroid, which can lead to hypothyroidism, a condition in which the thyroid does not make enough hormones for the body’s needs. Thyroid is a small gland at the base of the neck below the Adam’s apple. The thyroid gland is part of the endocrine system, which produces hormones that coordinate many of the body’s functions. The thyroid gland makes hormones that control metabolism. This includes the heart rate and how quickly the body uses calories from the foods consumed. Inflammation from Hashimoto’s disease, also known as chronic lymphocytic thyroiditis, often leads to an under-active thyroid gland (hypothyroidism). Hashimoto’s disease is the most common cause of hypothyroidism. It primarily affects middle-aged women but can also occur in men and women of any age and in children.
Signs and Symptoms of Hashimoto’s Thyroiditis
The first sign of the disease is often an enlarged thyroid, called a goiter. The goiter may cause the front of the neck to look swollen, a large goiter may make swallowing difficult. Hashimoto’s disease typically progresses slowly over years and causes chronic thyroid damage, leading to a drop in thyroid hormone levels in the blood. The signs and symptoms are mainly those of an under-active thyroid gland (hypothyroidism). Signs and symptoms of hypothyroidism include:
- Weight gain
- Fatigue and sluggishness
- Increased sensitivity to cold
- Constipation
- Paleness, dry skin
- A puffy face
- Brittle nails
- Hair loss
- Enlargement of the tongue
- Unexplained weight gain
- Muscle aches, tenderness and stiffness
- Joint pain and stiffness
- Muscle weakness
- Irregular, excessive or prolonged menstrual bleeding
- Depression
- Difficulty getting pregnant
- Memory lapses
Causes of Hashimoto’s Thyroiditis
Hashimoto’s disease is an autoimmune disorder in which the immune system creates antibodies that damage the thyroid gland. Doctors don’t know what causes the immune system to attack the thyroid gland. Some scientists think a virus or bacterium might trigger the response, while others believe a genetic flaw may be involved. A combination of factors, including heredity, sex and age may determine your likelihood of developing the disorder.
Detailed clinical data, elevated levels of TPO antibodies, biomarkers, TSH, T4, anti-thyroid autoantibodies, CT, MRI, genetic information, biopsy, pathology annotations associated with the Hashimoto’s Thyroiditis patient’s specimens is provided to a valued customer for research, development and drug discovery.
The Hashimoto’s Thyroiditis disease sera (serum), plasma and peripheral blood mononuclear cells (PBMC) biofluid samples are processed from patients peripheral whole-blood using customized collection and processing protocols provided by the researcher.
Bay Biosciences is a global leader in providing researchers with high quality, clinical grade, fully characterized human tissue samples, bio-specimens and human bio-fluid collections from cancer (tumor) tissue, cancer sera (serum), cancer plasma, cancer PBMC and human tissue samples from most other therapeutic areas and diseases.
Bay Biosciences maintains and manages it’s own bio-repository, human tissue bank (biobank) consisting of thousands of diseased samples (specimens) and from normal healthy donors available in all formats and types. Our biobank procures and stores fully consented, deidentified and institutional review boards (IRB) approved human tissue samples and matched controls.
All our human human tissue collections, human specimens and human bio-fluids are provided with detailed samples associated patient’s clinical data. This critical patient’s clinical data includes information relating to their past and current disease, treatment history, lifestyle choices, biomarkers and genetic information. Patient’s data is extremely valuable for researchers and is used to help identify new effective treatments (drug discovery & development) in oncology, other therapeutic areas and diseases. This clinical information is critical to demonstrate their impact, monitor the safety of medicines, testing & diagnostics, and generate new knowledge about the causes of disease and illness.
Bay Biosciences banks wide variety of human tissue samples and biological samples including cryogenically preserved -80°C, fresh, fresh frozen tissue samples, tumor tissue samples, FFPE’s, tissue slides, with matching human bio-fluids, whole blood and blood derived products such as serum, plasma and PBMC’s.
Bay Biosciences is a global leader in collecting and providing human tissue samples according to the researchers specified requirements and customized, tailor made collection protocols. Please contact us anytime to discuss your special research projects and customized human tissue sample requirements.
Bay Biosciences provides human tissue samples (human specimens) from diseased and normal healthy donors; including peripheral whole-blood, amniotic fluid, bronchoalveolar lavage fluid (BAL), sputum, pleural effusion, cerebrospinal fluid (CSF), serum (sera), plasma, peripheral blood mononuclear cells (PBMC’s), saliva, Buffy coat, urine, stool samples, aqueous humor, vitreous humor, kidney stones, renal calculi, nephrolithiasis, urolithiasis and other bodily fluids from most diseases including cancer. We can also procure most human bio-specimens and can do special collections and requests of human samples that are difficult to find. All our human tissue samples are procured through IRB approved clinical protocols and procedures.
In addition to the standard processing protocols Bay Biosciences can also provide human plasma, serum, PBMC bio-fluid samples using custom processing protocols, you can buy donor specific sample collections in higher volumes and specified sample aliquoting from us.
Bay Biosciences also provides human samples from normal healthy donors, volunteers, for controls and clinical research, contact us Now.
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