Bay Biosciences provides human kidney stone samples (urinal calculi) also called renal calculi, nephrolithiasis or urolithiasis specimens in phosphate-buffered saline solution (PBS) collected from 25 unique kidney patients between ages 18 years to 70 years old.

Moreover, detailed clinical data including donor’s age, sex, race, corresponding smoking and alcohol use information is provided to a valued diagnostic customer for research.

 

Kidney Stones Overview

Kidney stones, also known as renal calculi, nephrolithiasis, or urolithiasis, are hard deposits made of minerals and salts that form inside the kidneys. However, a definite, single cause of kidney stones is often lacking, although several factors may increase the risk of their development.

In particular, when the urine contains more crystal-forming substances, such as calcium, oxalate, and uric acid, than the fluid in the urine can dilute, kidney stones form. **Furthermore**, at the same time, the lack of substances in the urine that prevent crystals from sticking together creates an ideal environment for the formation of kidney stones inside the kidneys.

Types of Kidney Stones

Moreover, different types of kidney stones that form in the kidneys are as follows:

Firstly, calcium stones: Calcium stones are the most common type of kidney stones, typically occurring in the form of calcium oxalate. A substance that is produced daily by the liver or absorbed from the daily diet, oxalate is found in high levels in certain fruits and vegetables, as well as in nuts and chocolate.

Consequently, the concentration of calcium or oxalate in urine can be increased by dietary factors, high doses of vitamin D, intestinal bypass surgery, and several metabolic disorders, resulting in the formation of kidney stones.

  • Calcium stones may also occur in the form of calcium phosphate. In addition, this type of stone is more common in metabolic conditions, such as renal tubular acidosis. Furthermore, certain medications used to treat migraines or seizures may also be associated with this type of stone.
  • Struvite stones: On the other hand, struvite stones are formed in response to a urinary tract infection. Consequently, these stones can grow quickly and become quite large, sometimes presenting few symptoms or little warning.
  • Uric acid stones: Moreover, uric acid stones can form in individuals who lose excessive fluid due to chronic diarrhea or malabsorption, as well as in those who consume a high-protein diet, and among individuals with diabetes or metabolic syndrome. Similarly, cystine stones form in people with a hereditary disorder called cystinuria that causes the kidneys to excrete too much of a specific amino acid, which forms the kidney stones.
  • Cystine stones: Similarly, cystine stones form in people with a hereditary disorder called cystinuria that causes the kidneys to excrete too much of a specific amino acid, which forms the kidney stones.

Signs and Symptoms of Kidney Stones

Now, following are the common signs and symptoms of kidney stones:

  • Severe pain that you are unable to sit still or find a comfortable position
  • Blood in urine
  • Pain accompanied by nausea and vomiting
  • Pain accompanied by fever and chills
  • Blood in your urine
  • Infection
  • Difficulty passing urine

Biospecimens

Bay Biosciences is, indeed a global leader in providing researchers with high quality, clinical grade, fully characterized human tissue samples, bio-specimens, and human bio-fluid collections.

Specifically, aamples available include cancer (tumor) tissue, cancer serum, cancer plasma, cancer, peripheral blood mononuclear cells (PBMC). and human tissue samples from most other therapeutic areas and diseases.

Moreover, Bay Biosciences maintains and manages its own biorepository, the human tissue bank (biobank) consisting of thousands of diseased samples (specimens) and from normal healthy donors available in all formats and types.

In fact, our biobank procures and stores fully consented, de-identified and institutional review boards (IRB) approved human tissue samples and matched controls.

Additionally, all our human tissue collections, human specimens and human bio-fluids are provided with detailed, samples associated patient’s clinical data.

In particular, critical patient’s clinical data includes information relating to their past and current disease, treatment history, lifestyle choices, biomarkers, and genetic information.

Moreover, patient’s data is extremely valuable for researchers and is used to help identify new effective treatments (drug discovery & development) in oncology, and other therapeutic areas and diseases.

Specifically, Bay Biosciences banks wide variety of human tissue samples and biological samples, including cryogenically preserved at – 80°C.

For example fresh frozen tissue samples, tumor tissue samples, formalin-fixed paraffin-embedded (FFPE), tissue slides, with matching human bio-fluids, whole blood and blood-derived products such as serum, plasma and PBMC.

Furthermore, Bay Biosciences is a global leader in collecting and providing human tissue samples according to the specified requirements and customized, tailor-made collection protocols.

Therefore, please contact us anytime to discuss your special research projects and customized human tissue sample requirements.

Types of Biospecimens

Bay Biosciences provides human tissue samples (human specimens) from diseased and normal healthy donors which includes:

Customized Collections

Moreover, we can also procure most human bio-specimens, furthermore; we offer special collections and requests for human samples that are difficult to find. All our human tissue samples are procured through IRB-approved clinical protocols and procedures.

In addition to the standard processing protocols, Bay Biosciences can also provide human plasma, serum, and PBMC bio-fluid samples using custom processing protocols. Additionally you buy donor-specific collections in higher volumes and specified sample aliquots from us.

Furthermore, Bay Biosciences also provides human samples from normal healthy donors; volunteers, for controls and clinical research, contact us Now.

 

  • 日本のお客様は、ベイバイオサイエンスジャパンBay Biosciences Japanまたはhttp://baybiosciences-jp.com/contact/までご連絡ください。