Bay Biosciences provides fresh frozen high-quality, clinical grade serum (sera), plasma, and peripheral blood mononuclear cells (PBMC) samples from patients diagnosed with liver cancer.

Furthermore, they provide detailed patient information and clinical data associated with the liver cancer serum (sera), plasma, and peripheral blood mononuclear cells (PBMC) samples to a pharmaceutical customer for research, development, and discovery.

Function of the Liver

The largest internal organ in the body is, indeed, the liver. Furthermore, the liver plays a key role in the digestion of food. In fact, the body cannot live without the critical organ known as the liver. Additionally, the liver helps filter impurities and produces bile, which, in turn, assists the body in digesting food and processing fats.

Moreover, the liver performs some important functions, including:

  • Collecting and filtering blood from the intestines
  • Processing and storing needed nutrients absorbed by the intestines
  • Converting some nutrients into energy or into substances needed to repair and build tissue
  • Producing some of the body’s blood-clotting factors
  • Removing toxins from the body
  • Helping maintain the proper sugar level in the body

Liver Cancer Overview

Healthy cells change and grow out of control in the liver; consequently, they form a mass called a tumor, which leads to liver cancer. Moreover, tumors can be cancerous or benign. Specifically, a cancerous tumor is malignant, meaning it can grow and spread to other parts of the body. In contrast, a benign tumor grows but will not spread.

Furthermore, Primary Hepatic Cancer starts in the liver. Additionally, cirrhosis due to hepatitis B, hepatitis C, or excessive alcohol consumption leads to the development of liver cancer.

Other causes involve diseases like Non Fatty Alcoholic Liver (NAFLD) and other diseases. In addition, Hepatocellular Carcinoma (HCC), which makes up 80% of cases, is the most common type of liver cancer.

Furthermore, researchers classify liver cancer in two ways: primary liver cancer starts in the tissue of the liver. Specifically, doctors call the most common type of primary liver cancer hepatocellular carcinoma.

Moreover, the number of primary liver cancer cases in the United States has been increasing over the years, and diagnoses have more than tripled. Similarly, worldwide, medical professionals have seen liver cancer diagnoses increased increase by 75 percent in the past several years.

Secondary liver cancer originates in another part of the body and, consequently, infiltrates the liver. Moreover, doctors also call this type metastatic liver cancer. Furthermore, this condition is not liver cancer; rather, it is metastatic cancer from another organ. For example, if pancreatic, colon, stomach, breast, lung, or other cancers spread to the liver, they, nonetheless, retain the name of the organ where they originated.

Signs and Symptoms of Liver Cancer

Usually, you won’t notice any signs or symptoms of liver cancer; however, if doctors detect the tumor early as part of the screening process, you may be fortunate. Conversely, if the liver is swollen, here are some of the noticeable signs and symptoms of liver cancer:

  • Pain, especially at the top right of the abdominal area, near the right shoulder blade, or in the back
  • Fever 
  • Abdominal Swelling (ascites)
  • Jaundice, which appears as yellowing of the skin and eyes and occurs when the liver is not functioning properly
  • A hard lump under the ribs on the right side of the body, which could be the tumor or a sign that the liver has gotten enlarged (hepatomegaly) 
  • Nausea and vomiting

Additional Symptoms

Liver cirrhosis, rather than the tumor, may indeed cause some symptoms that people with liver cancer (HCC) experience. Specifically, these symptoms include abdominal swelling from fluid accumulation, called ascites, and, consequently, a need for more water tablets, called diuretics, to control the fluid accumulation.

Furthermore, hepatic encephalopathy (mental confusion) and bleeding from the esophagus or stomach, or, in addition, any worsening of the condition, may also indicate cancer.

Biospecimens

Bay Biosciences is, indeed a global leader in providing researchers with high quality, clinical grade, fully characterized human tissue samples, bio-specimens, and human bio-fluid collections.

Specifically, aamples available include cancer (tumor) tissue, cancer serum, cancer plasma, cancer, peripheral blood mononuclear cells (PBMC). and human tissue samples from most other therapeutic areas and diseases.

Moreover, Bay Biosciences maintains and manages its own biorepository, the human tissue bank (biobank) consisting of thousands of diseased samples (specimens) and from normal healthy donors available in all formats and types.

In fact, our biobank procures and stores fully consented, de-identified and institutional review boards (IRB) approved human tissue samples and matched controls.

Additionally, all our human tissue collections, human specimens and human bio-fluids are provided with detailed, samples associated patient’s clinical data.

In particular, critical patient’s clinical data includes information relating to their past and current disease, treatment history, lifestyle choices, biomarkers, and genetic information.

Moreover, patient’s data is extremely valuable for researchers and is used to help identify new effective treatments (drug discovery & development) in oncology, and other therapeutic areas and diseases.

Specifically, Bay Biosciences banks wide variety of human tissue samples and biological samples, including cryogenically preserved at – 80°C.

For example fresh frozen tissue samples, tumor tissue samples, formalin-fixed paraffin-embedded (FFPE), tissue slides, with matching human bio-fluids, whole blood and blood-derived products such as serum, plasma and PBMC.

Furthermore, Bay Biosciences is a global leader in collecting and providing human tissue samples according to the specified requirements and customized, tailor-made collection protocols.

Therefore, please contact us anytime to discuss your special research projects and customized human tissue sample requirements.

Types of Biospecimens

Bay Biosciences provides human tissue samples (human specimens) from diseased and normal healthy donors which includes:

Customized Collections

Moreover, we can also procure most human bio-specimens. Furthermore; we offer special collections and requests for human samples that are difficult to find. All our human tissue samples are procured through IRB-approved clinical protocols and procedures.

In addition to the standard processing protocols, Bay Biosciences can also provide human plasma, serum, and PBMC bio-fluid samples using custom processing protocols. Additionally you buy donor-specific collections in higher volumes and specified sample aliquots from us.

Furthermore, Bay Biosciences also provides human samples from normal healthy donors; volunteers, for controls and clinical research, contact us Now.

 

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