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Muscle Stiffness Overview

Muscle stiffness is when your muscles feel tight and you find it more difficult to move than you usually do, especially after rest. Muscles stiffness can also be accompanied by pain, cramping, and discomfort. Muscle stiffness may occur after overuse of a particular muscle, or it may indicate an underlying condition.

It is usually not a cause for concern and can be treated with home remedies and stretching. Muscle stiffness usually goes away on its own. You may find relief with regular exercise and stretching. In some cases, muscle stiffness can be a sign of something more serious, especially if there are other symptoms present.

Types of Muscle Stiffness

There are three types of muscle: skeletal, cardiac, and smooth. Muscle stiffness primarily affects skeletal muscle, which is a voluntarily-controlled type of muscle that enables humans to move and perform daily activities.

In general, these actions are possible after a signal from the nervous system stimulates contraction of the skeletal muscle, resulting in movement. If any problems interfere with the communication between the nervous system and the muscle cells, the muscles may remain contracted and result in stiffness.

Causes of Muscle Stiffness

Muscle stiffness is generally characterized by soreness and difficulty moving, sometimes accompanied by cramps, pain, or weakness. Most often, muscle stiffness will occur in the morning and last for less than 30 minutes after waking up or for a couple of days after engaging in new or more challenging exercise.

Other signs and symptoms accompanying muscle stiffness are typically dependent upon the specific causes and location of the stiffness. Muscle stiffness may interfere with walking (i.e., gait), causing a slower, more difficult, and often painful gait.

If muscle spasms accompany the stiffness, the spasms may be triggered by intense emotions, loud noises, or sudden movements. In cases of neuromuscular disorder, muscle stiffness may also be accompanied by curvature of the lower spine  and nervous system problems, such as difficulty balancing, numbness or tingling, drooping eyelids, difficulty swallowing, or difficulty breathing.

Bay Biosciences is a global leader in providing researchers with high quality, clinical grade, fully characterized human tissue samples, bio-specimens and human bio-fluid collections. 

We have cancer (tumor) tissue, cancer serumcancer plasma cancer PBMC and human tissue samples from most other therapeutic areas and diseases.

Our company Bay Biosciences maintains and manages its own bio-repository, human tissue bank (biobank) consisting of thousands of diseased samples (specimens) and from normal healthy donors available in all formats and types.

Our biobank procures and stores fully consented, deidentified and institutional review boards (IRB) approved human tissue samples and matched controls.

All our human tissue collections, human specimens and human bio-fluids are provided with detailed samples associated patient’s clinical data.

This critical patient’s clinical data includes information relating to their past and current disease, treatment history, lifestyle choices, biomarkers and genetic information.

Patient’s data is extremely valuable for researchers and is used to help identify new effective treatments (drug discovery & development) in oncology, other therapeutic areas and diseases. 

This clinical information is critical to demonstrate their impact, monitor the safety of medicines, testing & diagnostics, and generate new knowledge about the causes of disease and illness. 

Bay Biosciences banks wide variety of human tissue samples and biological samples including cryogenically preserved at – 80°C.

Including fresh frozen tissue samplestumor tissue samples, FFPE’s, tissue slides, with matching human bio-fluids, whole blood and blood derived products such as serumplasma and PBMC’s.

Bay Biosciences is a global leader in collecting and providing human tissue samples according to the researchers specified requirements and customized, tailor-made collection protocols.

Please contact us anytime to discuss your special research projects and customized human tissue sample requirements.

Bay Biosciences provides human tissue samples (human specimens) from diseased and normal healthy donors which includes:

We can also procure most human bio-specimens and can-do special collections and requests of human samples that are difficult to find. All our human tissue samples are procured through IRB approved clinical protocols and procedures. 

In addition to the standard processing protocols Bay Biosciences can also provide human plasmaserum, PBMC bio-fluid samples using custom processing protocols, you can buy donor specific sample collections in higher volumes and specified sample aliquots from us.

 Bay Biosciences also provides human samples from normal healthy donors, volunteers, for controls and clinical research, contact us Now.

 

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