Bay Biosciences provides high quality, clinical grade, matched cryogenically preserved sera (serum), plasma, peripheral blood mononuclear cells (PBMC) biofluid samples from patients diagnosed with Post-Traumatic Stress Disorder.

Moreover, the sera (serum), plasma and PBMC bio-fluid specimens are processed from Post-Traumatic stress disorder patient’s peripheral whole-blood using customized collection and processing protocols.

 

Post-Traumatic Stress Disorder (PTSD) Overview

Post-traumatic stress disorder (PTSD) is a psychiatric disorder that may occur in patients who have experienced or witnessed a traumatic event, such as a natural disaster, a serious accident, a terrorist act, war/combat, or rape.

Alternatively, it may also affect those who have been threatened with death, sexual violence, or serious injury.

Furthermore, patients with posttraumatic stress disorder (PTSD) have intense, disturbing thoughts and feelings related to their experience that last long after the traumatic event has ended.

In addition, they may relive the event through flashbacks or nightmares; moreover, they may feel sadness, fear, or anger. Additionally, they may feel detached or estranged from other people.

Consequently, patients with PTSD may avoid situations or people that remind them of the traumatic event. As a result, they may have strong negative reactions to something as ordinary as a loud noise or an accidental touch.

Signs and Symptoms of Post-Traumatic Stress Disorder (PTSD)

Most often, the signs and symptoms of Post-Traumatic Stress Disorder (PTSD) begin within three months of the traumatic event. However, in some cases, they don’t begin until years later. Moreover, the severity and duration of the illness can vary.
For instance, some people recover within six months, while others have it much longer. Additionally, the intensity of PTSD symptoms may vary. Specifically, you may have more symptoms when you feel stress in general, or when you encounter a specific reminder about what happened. Furthermore, young children with PTSD may have delayed development in areas such as toilet training, motor skills, and language.

Symptoms Categories

Following are the four main categories that the symptoms of PTSD often are grouped into:

  • Firstly, reliving: Patients with PTSD repeatedly relive the ordeal through thoughts and memories of the trauma. Specifically, these may include flashbacks, hallucinations, and nightmares. Moreover, they also may feel great distress when certain things remind them of the trauma, such as the anniversary date of the event.
  • Secondly, avoiding: The PTSD patient must avoid people, places, thoughts, or situations that may remind them of the trauma. Consequently, this can lead to feelings of detachment and isolation from family and friends, as well as a loss of interest in activities that the person once enjoyed.
  • Thirdly, increased arousal: These include excessive emotions; problems relating to others, including feeling or showing affection; difficulty falling or staying asleep; irritability; outbursts of anger; difficulty concentrating; and being “jumpy” or easily startled. In addition, the person may also suffer physical symptoms, such as increased high blood pressure (Hypertension) and heart rate, rapid breathing, muscle tension, nausea and diarrhea.
  • Finally, negative cognitions and mood: Mood swings and negative conditions refers to thoughts and feelings related to blame, estrangement, and memories of the traumatic event.

Causes of Post-Traumatic Stress Disorder (PTSD)

Post-traumatic stress disorder (PTSD) can develop when someone go through, see or learn about an event involving actual or threatened death, serious injury or sexual violence.

However, researchers are not sure why some people get Post-traumatic stress disorder (PTSD). As with most mental health problems, PTSD is probably caused by a complex mix of factors.

In addition, following are some of the common causes that can contribute to PTSD:

  • Firstly, traumatic and stressful experiences, including the amount and severity of trauma you’ve gone through in your life
  • Secondly, inherited mental health risks, such as a family history of anxiety and depression.
  • Moreover, inherited features of a persons personality, or an individual’s temperament.
  • Finally, how the brain regulates the chemicals and hormones the body releases in response to stress.

Types of Post-Traumatic Stress Disorder (PTSD) Events

Following are the most common events leading to the development of PTSD:

  • Traumatic Event
  • Combat exposure
  • Childhood physical abuse
  • Sexual violence
  • Physical assault
  • Being threatened with a weapon
  • An accident
  • Violence

Additionally, many other traumatic events also can lead to PTSD. For instance, such events include fire, natural disaster, mugging, robbery, plane crash, torture, kidnapping, life-threatening medical diagnosis, terrorist attack, and other extreme or life-threatening events.

Types of Biospecimens

Bay Biosciences provides human tissue samples (human specimens) and human biofluids from diseased and normal healthy donors which includes:

Moreover, we can also procure most human biospecimens and human biofluids, special collections and requests for human samples that are difficult to find. All our human tissue samples and human biofluids are procured through IRB-approved clinical protocols and procedures.

In addition to the standard processing protocols, Bay Biosciences can also provide human biofluids such as  human plasma, human serum, and human PBMCs bio-fluid samples using custom processing protocols; you buy donor-specific collections in higher volumes and specified sample aliquots from us.

Bay Biosciences also provides human biospecimens from normal healthy donors; volunteers, for controls and clinical research, Contact us Now.