Bay Biosciences provides high quality, clinical grade, FFPE tissue blocks and matched cryogenically preserved sera (serum), plasma, peripheral blood mononuclear cells (PBMC) biofluid samples from patients diagnosed with Rheumatoid Arthritis (RA).
The sera (serum), plasma and PBMC biofluid specimens are processed from rheumatoid arthritis patient’s peripheral whole-blood using customized collection and processing protocols.
The rheumatoid arthritis tissue and matched biofluid samples are collected from unique patients diagnosed with rheumatoid arthritis and are provided to a valued pharmaceutical customer for research, diagnostics, discovery and drug development.
Detailed clinical data, rheumatoid arthritis patient’s history, symptoms, complete blood count (CBC), rheumatoid factor test, serology, MRI, biopsy tissue, histopathology information, elevated biomarker levels, genetic and metabolic information associated with rheumatoid arthritis specimens is provided to a valued customer for research, development and drug discovery.
The rheumatoid arthritis sera (serum), plasma and peripheral blood mononuclear cells (PBMC) biofluids are processed from patients peripheral whole-blood using customized collection and processing protocols.
Rheumatoid Arthritis Overview
Rheumatoid Arthritis (RA) is an autoimmune and a chronic inflammatory disease, which means that your immune system attacks healthy cells and tissue in your body by mistake, causing inflammation (painful swelling) in the affected parts of the body. Rheumatoid Arthritis can affect more than just your joints. In some people, the condition can damage a wide variety of body systems, including the skin, eyes, lungs, heart and blood vessels.
Unlike the wear-and-tear damage of osteoarthritis, rheumatoid arthritis affects the lining of the joints, causing a painful swelling that can eventually result in bone erosion and joint deformity. RA mainly attacks the joints, usually many joints at once, it commonly affects joints in the hands, wrists, and knees. In a joint with RA, the lining of the joint becomes inflamed, causing damage to joint tissue. This tissue damage can cause long-lasting or chronic pain, unsteadiness (lack of balance), and deformity (misshapenness).
The inflammation associated with Rheumatoid Arthritis is what can damage other parts of the body as well, and cause problems in organs such as the lungs, heart, and eyes. There are times when symptoms get worse, known as flares, and times when symptoms get better, known as remission.
Signs and symptoms of Rheumatoid Arthritis
Signs and symptoms of RA include:
- Pain or aching in more than one joint
- Stiffness in more than one joint
- Tenderness and swelling in more than one joint
- The same symptoms on both sides of the body (such as in both hands or both knees)
- Weight loss
- Fever
- Fatigue or tiredness
- Weakness
People born with specific genes are more likely to develop Rheumatoid Arthritis. These genes, called HLA (human leukocyte antigen) class II genotypes, can also make the arthritis worse. The risk of Rheumatoid Arthritis may be highest when people with these genes are exposed to certain environmental factors like smoking or obesity.
Bay Biosciences is a global leader in providing researchers with high quality, clinical grade, fully characterized human tissue samples, bio-specimens and human bio-fluid collections from cancer (tumor) tissue, cancer serum, cancer plasma cancer PBMC and human tissue samples from most other therapeutic areas and diseases.
Bay Biosciences maintains and manages it’s own bio-repository, human tissue bank (biobank) consisting of thousands of diseased samples (specimens) and from normal healthy donors available in all formats and types. Our biobank procures and stores fully consented, deidentified and institutional review boards (IRB) approved human tissue samples and matched controls.
All our human human tissue collections, human specimens and human bio-fluids are provided with detailed samples associated patient’s clinical data. This critical patient’s clinical data includes information relating to their past and current disease, treatment history, lifestyle choices, biomarkers and genetic information.
Patient’s data is extremely valuable for researchers and is used to help identify new effective treatments (drug discovery & development) in oncology, other therapeutic areas and diseases. This clinical information is critical to demonstrate their impact, monitor the safety of medicines, testing & diagnostics, and generate new knowledge about the causes of disease and illness.
Bay Biosciences banks wide variety of human tissue samples and biological samples including cryogenically preserved -80°C, fresh, fresh frozen tissue samples, tumor tissue samples, FFPE’s, tissue slides, with matching human bio-fluids, whole blood and blood derived products such as serum, plasma and PBMC’s.
Bay Biosciences is a global leader in collecting and providing human tissue samples according to the researchers specified requirements and customized, tailor made collection protocols. Please contact us anytime to discuss your special research projects and customized human tissue sample requirements.
Bay Biosciences provides human tissue samples (human specimens) from diseased and normal healthy donors; including peripheral whole-blood, amniotic fluid, bronchoalveolar lavage fluid (BAL), sputum, pleural effusion, cerebrospinal fluid (CSF), serum (sera), plasma, peripheral blood mononuclear cells (PBMC’s), saliva, Buffy coat, urine, stool samples, aqueous humor, vitreous humor, kidney stones, renal calculi, nephrolithiasis, urolithiasis and other bodily fluids from most diseases including cancer.
We can also procure most human bio-specimens and can do special collections and requests of human samples that are difficult to find. All our human tissue samples are procured through IRB approved clinical protocols and procedures.
In addition to the standard processing protocols Bay Biosciences can also provide human plasma, serum, PBMC bio-fluid samples using custom processing protocols, you can buy donor specific sample collections in higher volumes and specified sample aliquoting from us.
Bay Biosciences also provides human samples from normal healthy donors, volunteers, for controls and clinical research, contact us Now.
日本のお客様は、ベイバイオサイエンスジャパンBay Biosciences Japanまたはhttp://baybiosciences-jp.com/contact/までご連絡ください。