Bay Biosciences provides high quality, clinical grade bio-samples, cryogenically preserved human skeletal muscle biopsy tissue samples from the vastus lateralis (quadricep muscle) with matching sera (serum) and plasma biofluid samples.

 The vastus lateralis also called the is the largest and most powerful part of the quadriceps femoris, a muscle in the thigh. The skeletal muscles selected for biopsy sampling are the bicep (upper arm muscle), deltoid (shoulder muscle), or quadriceps (thigh muscle). Skeletal muscle biopsy specimens are provided to a valued pharmaceutical customer for research, development and  drug discovery.

Detailed clinical data, biomarkers, genetic information associated with the skeletal muscle biopsy tissue samples, pathology annotations is provided to a valued customer for research, development and drug discovery.

Human muscle biopsy tissue is used to assess the musculoskeletal system for abnormalities. Various disease processes can cause muscle weakness or pain. These conditions may be related to problems with the nervous system, connective tissue, vascular system, or musculoskeletal system.  A muscle biopsy helps determine the source of the disease process, which ensures the proper treatment. Muscle biopsy tissue samples are also used to diagnose neuromuscular disorders, infections that affect the muscle, and other abnormalities in the muscle tissue.

Following are some of the diseases diagnosed by muscle biopsy tissue:

  • Muscular Dystrophy (MD): A broad term that describes a genetic (inherited) disorder of the muscles. Muscular dystrophy affects skeletal muscles and other organ systems. When the muscles break down, fatty deposits replace them over time. There are many different types of muscular dystrophy.
  • Duchenne Muscular Dystrophy (DMD): The most common form of muscular dystrophy. DMD usually affects only male patients.
  •  Becker Muscular Dystrophy: Similar to Duchenne muscular dystrophy (DMD), but usually more mild and symptoms start later in life.
  • Trichinosis: An infection caused by a parasite that lives in raw meat. Symptoms may include muscle pain.
  • Toxoplasmosis: An infection caused by a parasite that invades the tissue and can damage the central nervous system, especially in infants.
  • Myasthenia Gravis (MG): A complex, autoimmune disorder in which antibodies destroy neuromuscular connections. This causes problems with the nerves that communicate with muscles. MG affects the voluntary muscles of the body, especially the eyes, mouth, throat, and limbs.
  • Polymyosiyis: A chronic disease involving skeletal muscles
  • Dermatomyositis: A collagen disorder that causes inflammation to the skin, muscles, and subcutaneous tissue, often resulting in weakened muscles.
  • Amyotrophic Lateral Sclerosis (ALS): Also known as Lou Gehrig disease, ALS is a disease that attacks the nerves signaling voluntary muscle movement, eventually causing paralysis.
  • Friedreich Ataxia: An inherited, genetic disorder that involves balance and coordination.

Biospecimens

biospecimens

Bay Biosciences is a global leader in providing researchers with high quality, clinical grade, fully characterized human tissue samples, bio-specimens, and human bio-fluid collections.

Moreover, human biospecimens are available including tumor tissue, serum, plasma and PBMC samples from most other therapeutic areas.

Furthermore, Bay Biosciences maintains and manages its own biorepository, the human tissue bank (biobank) consisting of thousands of diseased samples (specimens) and likewise normal healthy donors for controls. Additionally, available in all formats and types.

In fact, our biobank procures and stores fully consented, de-identified and institutional review boards (IRB) approved human tissue samples, human biofluids such as serum samples, plasma samples from various diseases and matched controls.

Also, all our human tissue collections, human biospecimens and human biofluids are provided with detailed, samples associated patient’s clinical data.

In fact, this critical patient’s clinical data includes information relating to their past and current disease, treatment history, lifestyle choices, biomarkers, and genetic information.

Additionally, researchers find the patient’s data associated with the human biospecimens extremely valuable and use it to help identify new effective treatments (drug discovery & development) in oncology, as well as in other therapeutic areas and diseases.

Bay Biosciences banks wide variety of human tissue samples and human biological samples, including fresh frozen human biospecimens cryogenically preserved at – 80°C.

For example fresh frozen tissue samples, tumor tissue samples, formalin-fixed paraffin-embedded (FFPE), tissue slides, with matching human bio-fluids, whole blood and blood-derived products such as human serum, human plasma and human PBMCs.

Bay Biosciences is a global leader in collecting and providing human tissue samples according to the specified requirements and customized, tailor-made collection protocols.

Please contact us anytime to discuss your special research projects and customized human tissue sample requirements.

Types of Biospecimens

Bay Biosciences provides human tissue samples (human specimens) and human biofluids from diseased and normal healthy donors which includes:

Moreover, we can also procure most human biospecimens and human biofluids, special collections and requests for human samples that are difficult to find. All our human tissue samples and human biofluids are procured through IRB-approved clinical protocols and procedures.

In addition to the standard processing protocols, Bay Biosciences can also provide human biofluids such as  human plasma, human serum, and human PBMCs bio-fluid samples using custom processing protocols; you buy donor-specific collections in higher volumes and specified sample aliquots from us.

Bay Biosciences also provides human biospecimens from normal healthy donors; volunteers, for controls and clinical research, Contact us Now.