Bay Biosciences provides fresh frozen clinical grade tissue samples, FFPE Blocks with matched high quality serum (sera), plasma and peripheral blood mononuclear cells (PBMC) biofluid samples from systemic lupus erythematosus (SLE) patient’s.

Moreover, samples are collected from unique multi-ethnic systemic lupus erythematosus (SLE) patients at multiple collection sites for development, drug discovery and research.

In addition, detailed clinical data associated with serum, plasma and PBMC biofluids is provided to a valued customer for research, discovery and development.

Systemic Lupus Erythematosus

Systemic Lupus Erythematosus (SLE) is, indeed, an autoimmune and a chronic inflammatory disease that causes multi-organ injury, including damage to the kidneys, blood, brain, and skin. Specifically, an autoimmune disease is a condition in which the body’s immune system mistakenly attacks its own healthy tissue in many parts of the body, consequently causing widespread inflammation and tissue damage in the affected organs.

Furthermore, the immune system normally guards against germs like bacteria and viruses. When it senses these foreign invaders, it sends out an army of fighter cells to attack them.

Typically, the immune system can tell the difference between foreign cells and the body’s own cells. However, in an autoimmune disease, the immune system mistakenly perceives part of the body, such as the joints or skin, as foreign. As a result, it releases proteins called autoantibodies that start attacking healthy cells.

Moreover, systemic lupus erythematosus (SLE) can affect the joints, skin, brain, heart, liver, lungs, kidneys, and blood vessels. Notably, symptoms vary between people and may range from mild to severe.

 

 

In addition, common symptoms include a rash, which is most commonly on the face, fever, chest pain, hair loss, painful and swollen joints, swollen lymph nodes, mouth ulcers, tiredness, and fatigue.

Moreover, features of SLE include periods of flare-up and remission, dysregulation of the immune system and development of autoantibodies. Furthermore, at the more severe end of the spectrum, SLE can cause nephritis, neurological problems, anemia and thrombocytopaenia (low level of platelets). Therefore, SLE may be difficult to diagnose because its early signs and symptoms are not specific and can look like signs and symptoms of other diseases.

Biospecimens

biospecimens

Bay Biosciences is a global leader in providing researchers with high quality, clinical grade, fully characterized human tissue samples, bio-specimens, and human bio-fluid collections.

Moreover, human biospecimens are available including tumor tissue, serum, plasma and PBMC Samples from most other therapeutic areas.

Furthermore, Bay Biosciences maintains and manages its own biorepository, the human tissue bank (biobank) consisting of thousands of diseased samples (specimens) and likewise normal healthy donors for controls. Additionally, available in all formats and types.

In fact, our biobank procures and stores fully consented, de-identified and institutional review boards (IRB) approved human tissue samples, human biofluids such as serum samples, plasma samples from various diseases and matched controls.

Also, all our human tissue collections, human biospecimens and human biofluids are provided with detailed, samples associated patient’s clinical data.

In fact, this critical patient’s clinical data includes information relating to their past and current disease, treatment history, lifestyle choices, biomarkers, and genetic information.

Additionally, researchers find the patient’s data associated with the human biospecimens extremely valuable and use it to help identify new effective treatments (drug discovery & development) in oncology, as well as in other therapeutic areas and diseases.

Bay Biosciences banks wide variety of human tissue samples and human biological samples, including fresh frozen human biospecimens cryogenically preserved at – 80°C.

For example fresh frozen tissue samples, tumor tissue samples, formalin-fixed paraffin-embedded (FFPE), tissue slides, with matching human bio-fluids, whole blood and blood-derived products such as human serum, human plasma and human PBMCs.

Bay Biosciences is a global leader in collecting and providing human tissue samples according to the specified requirements and customized, tailor-made collection protocols.

Please contact us anytime to discuss your special research projects and customized human tissue sample requirements.

Types of Biospecimens

Bay Biosciences provides human tissue samples (human specimens) and human biofluids from diseased and normal healthy donors which includes:

Moreover, we can also procure most human biospecimens and human biofluids, special collections and requests for human samples that are difficult to find. All our human tissue samples and human biofluids are procured through IRB-approved clinical protocols and procedures.

In addition to the standard processing protocols, Bay Biosciences can also provide human biofluids such as  human plasma, human serum, and human PBMCs bio-fluid samples using custom processing protocols. you buy donor-specific collections in higher volumes and specified sample aliquots from us in multiple format and sets.

Bay Biosciences also provides human biospecimens from normal healthy donors; volunteers, for controls and clinical research, Contact us Now.