Bay Biosciences provides high quality, clinical grade fresh frozen high-grade bladder cancer tumor tissue specimens, with matching cryogenically preserved serum (sera), plasma, peripheral blood mononuclear cells (PBMC’s) biofluid samples. The serum (sera), plasma and PBMC biofluid samples are processed from patients whole blood following customized protocols, from unique bladder cancer patients to a valued pharmaceutical customer for drug discovery, research and development.
Bladder Cancer Overview
Bladder cancer is a type of cancer that begins in the cells of the bladder. The bladder is a hollow muscular organ in the lower abdomen that stores urine. Bladder cancer most often begins in the Urothelial cells that line the inside of the bladder. Urothelial cells are also found in the kidneys and the tubes known as ureters that connect the kidneys to the bladder. Urothelial cancer can happen in the kidneys and ureters also, but it’s more common in the bladder.
High-grade tumors tends to grow more aggressively than low-grade tumors and may be more likely to spread or metastasize to the muscular wall of the bladder and other tissues and organs in the body.
Bladder cancer begins when cells in the bladder develop changes or mutations in their DNA.
Cell’s DNA contains instructions that tell the cell what to do, the changes tell the cell to multiply rapidly and to go on living when healthy cells would die. The abnormal cells form a tumor that can invade and destroy normal body tissue. In time, the abnormal cells can break away and spread or metastasize through the body. Most bladder cancers are diagnosed at an early stage, when the cancer is highly treatable. But even early-stage bladder cancers can come back after successful treatment.
Signs and Symptoms of Bladder Cancer
Bladder cancer signs and symptoms may include:
- Blood in urine or hematuria, which may cause urine to appear bright red or brown colored.
- Frequent urination
- Painful urination
- Back pain
Detailed clinical data, biomarker information including cystoscopy, CT, urine cytology, biopsy & pathology annotations, and patients history associated with the high grade Bladder cancer samples is provided to a valued customer for drug discovery, development and research. The serum (sera), plasma and PBMC biofluid samples were processed using customized protocols provided by the researcher.
Bay Biosciences is a global leader in providing researchers with high quality, clinical grade, fully characterized human tissue samples, bio-specimens and human bio-fluid collections from cancer (tumor) tissue, cancer sera (serum), cancer plasma, cancer PBMC and human tissue samples from most other therapeutic areas and diseases.
Bay Biosciences maintains and manages it’s own bio-repository, human tissue bank (biobank) consisting of thousands of diseased samples (specimens) and from normal healthy donors available in all formats and types. Our biobank procures and stores fully consented, deidentified and institutional review boards (IRB) approved human tissue samples and matched controls.
All our human human tissue collections, human specimens and human bio-fluids are provided with detailed samples associated patient’s clinical data. This critical patient’s clinical data includes information relating to their past and current disease, treatment history, lifestyle choices, biomarkers and genetic information. Patient’s data is extremely valuable for researchers and is used to help identify new effective treatments (drug discovery & development) in oncology, other therapeutic areas and diseases. This clinical information is critical to demonstrate their impact, monitor the safety of medicines, testing & diagnostics, and generate new knowledge about the causes of disease and illness.
Bay Biosciences banks wide variety of human tissue samples and biological samples including cryogenically preserved -80°C, fresh, fresh frozen tissue samples, tumor tissue samples, FFPE’s, tissue slides, with matching human bio-fluids, whole blood and blood derived products such as serum, plasma and PBMC’s.
Bay Biosciences is a global leader in collecting and providing human tissue samples according to the researchers specified requirements and customized, tailor made collection protocols. Please contact us anytime to discuss your special research projects and customized human tissue sample requirements.
Bay Biosciences provides human tissue samples (human specimens) from diseased and normal healthy donors; including peripheral whole-blood, amniotic fluid, bronchoalveolar lavage fluid (BAL), sputum, pleural effusion, cerebrospinal fluid (CSF), serum (sera), plasma, peripheral blood mononuclear cells (PBMC’s), saliva, Buffy coat, urine, stool samples, aqueous humor, vitreous humor, kidney stones, renal calculi, nephrolithiasis, urolithiasis and other bodily fluids from most diseases including cancer. We can also procure most human bio-specimens and can do special collections and requests of human samples that are difficult to find. All our human tissue samples are procured through IRB approved clinical protocols and procedures.
In addition to the standard processing protocols Bay Biosciences can also provide human plasma, serum, PBMC bio-fluid samples using custom processing protocols, you can buy donor specific sample collections in higher volumes and specified sample aliquoting from us. Bay Biosciences also provides human samples from normal healthy donors, volunteers, for controls and clinical research, contact us Now.
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