Bay Biosciences provides 2 ml fresh frozen bronchoalveolar lavage fluid (BAL) samples, processed into pellet and cell-free BAL for research. The BAL samples are collected from unique patients diagnosed with Idiopathic pulmonary fibrosis (IPF) disease.
Detailed clinical data, serology, pathology annotations including patient’s biomarkers, corresponding diagnostic test values associated with the BAL samples are provided to a valued pharmaceutical customer for research.
Idiopathic Pulmonary Fibrosis
Idiopathic pulmonary fibrosis (IPF) is a type of lung disease that results in scarring (fibrosis) of the lungs for an unknown reason. Over time, the scarring gets worse which causes shortness of breath and it becomes hard to take in a deep breath and the lungs cannot take in enough oxygen.
IPF is a form of interstitial lung disease, primarily involving the interstitium (the tissue and space around the air sacs of the lungs), and not directly affecting the airways or blood vessels. There are many other kinds of interstitial lung disease that can also cause inflammation and/or fibrosis, and these are treated differently.
Signs and Symptoms of Idiopathic Pulmonary Fibrosis
Following are the common signs and symptoms symptoms of Idiopathic Pulmonary Fibrosis (IPF) are:
- Shortness of breath (also known as dyspnea or breathlessness): Usually the shortness of breath caused by IPF first appears during exercise. Shortness of breath can affect day-to-day activities such as showering, climbing stairs, getting dressed and eating. As scarring in the lungs gets worse, breathlessness may prevent all activities.
- Chronic cough: About 85% of people with Idiopathic Pulmonary Fibrosis (IPF) have a chronic cough that has lasts longer than 8 weeks. This is often a dry cough, but some people may also cough up sputum or phlegm.
Other symptoms may include:
- Chest pain or tightness
- Unexplained weight loss
- Loss of appetite
- Fatigue, tiredness and loss of energy
- Change of finger shape called “clubbing”
Causes of Idiopathic Pulmonary Fibrosis
The cause of idiopathic pulmonary fibrosis (IPF) are unknown and not completely understood. “Idiopathic” means of unknown cause. Common risk factors for IPF include:
- Genetics (family history): Up to 20% of people with IPF have another family member with an interstitial lung disease. If more than one member of your family has IPF, the disease is called familial pulmonary fibrosis.
- Cigarette smoking: Approximately 75% of people with IPF are current or previous cigarette smokers.
- Acid reflux: Gastroesophageal reflux disease GERD. Approximately 75% of people with IPF have symptoms of acid reflux or heartburn.
- Male sex: Approximately 75% of patients with IPF are male.
- Age: Almost all patients with IPF are over the age of 50 years.
Bay Biosciences is a global leader in providing researchers with high quality, clinical grade, fully characterized human tissue samples, bio-specimens and human bio-fluid collections from cancer (tumor) tissue, cancer serum, cancer plasma cancer PBMC and human tissue samples from most other therapeutic areas and diseases.
Bay Biosciences maintains and manages it’s own bio-repository, human tissue bank (biobank) consisting of thousands of diseased samples (specimens) and from normal healthy donors available in all formats and types. Our biobank procures and stores fully consented, deidentified and institutional review boards (IRB) approved human tissue samples and matched controls.
All our human human tissue collections, human specimens and human bio-fluids are provided with detailed samples associated patient’s clinical data. This critical patient’s clinical data includes information relating to their past and current disease, treatment history, lifestyle choices, biomarkers and genetic information. Patient’s data is extremely valuable for researchers and is used to help identify new effective treatments (drug discovery & development) in oncology, other therapeutic areas and diseases. This clinical information is critical to demonstrate their impact, monitor the safety of medicines, testing & diagnostics, and generate new knowledge about the causes of disease and illness.
Bay Biosciences banks wide variety of human tissue samples and biological samples including cryogenically preserved -80°C, fresh, fresh frozen tissue samples, tumor tissue samples, FFPE’s, tissue slides, with matching human bio-fluids, whole blood and blood derived products such as serum, plasma and PBMC’s.
Bay Biosciences is a global leader in collecting and providing human tissue samples according to the researchers specified requirements and customized, tailor made collection protocols. Please contact us anytime to discuss your special research projects and customized human tissue sample requirements.
Bay Biosciences provides human tissue samples (human specimens) from diseased and normal healthy donors; including peripheral whole-blood, amniotic fluid, bronchoalveolar lavage fluid (BAL), sputum, pleural effusion, cerebrospinal fluid (CSF), serum (sera), plasma, peripheral blood mononuclear cells (PBMC’s), saliva, Buffy coat, urine, stool samples, aqueous humor, vitreous humor, kidney stones, renal calculi, nephrolithiasis, urolithiasis and other bodily fluids from most diseases including cancer. We can also procure most human bio-specimens and can do special collections and requests of human samples that are difficult to find. All our human tissue samples are procured through IRB approved clinical protocols and procedures.
In addition to the standard processing protocols Bay Biosciences can also provide human plasma, serum, PBMC bio-fluid samples using custom processing protocols, you can buy donor specific sample collections in higher volumes and specified sample aliquoting from us. Bay Biosciences also provides human samples from normal healthy donors, volunteers, for controls and clinical research, contact us Now.
日本のお客様は、ベイバイオサイエンスジャパンBay Biosciences Japanまたはhttp://baybiosciences-jp.com/contact/までご連絡ください。