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Bad Breath Overview

Bad breath affects an estimated 25 percent of people. There are a number of possible causes of bad breath also known as halitosis, but the vast majority come down to oral hygiene.

Also halitosis (bad breath) is known as fetor oris. Halitosis can cause significant worry, embarrassment, and anxiety but it is relatively easy to remedy.

Fast Facts on Bad Breath

Following are some key points about bad breath:

  • Bad breath is estimated to affect 1 in 4 people globally.
  • The most common cause of halitosis is bad oral hygiene.
  • If particles of food are left in the mouth, their breakdown by bacteria produces sulfur compounds.
  • Keeping the mouth hydrated can reduce mouth odor.
  • The best treatment for bad breath is regular brushing, flossing, and hydration.


What is Bad Breath?

Bad breath is a common problem that can cause significant psychological distress. Moreover, there are a number of potential causes and treatments available.

In fact anyone can suffer from bad breath. It is estimated that 1 in 4 people have bad breath on a regular basis.

Also, halitosis is the third most common reason that people seek dental care, after tooth decay and gum disease.

Simple home remedies and lifestyle changes, such as improved dental hygiene and quitting smoking, can often remove the issue. If bad breath persists, however, it is advisable to visit a doctor to check for underlying causes.

Causes of Bad Breath

Potential causes of bad breath include:

  • Tobacco: Tobacco products cause their own types of mouth odor. Additionally, they increase the chances of gum disease which can also cause bad breath.
  • Food: The breakdown of food particles stuck in the teeth can cause odors. Some foods such as onions and garlic can also cause bad breath. After they are digested, their breakdown products are carried in the blood to the lungs where they can affect the breath.
  • Dry mouth: Saliva naturally cleans the mouth. If the mouth is naturally dry or dry due to a specific disease, such as xerostomia, odors can build up.
  • Dental hygiene: Brushing and flossing ensure the removal of small particles of food that can build up and slowly break down, producing odor. A film of bacteria called plaque builds up if brushing is not regular. This plaque can irritate the gums and cause inflammation between the teeth and gums called periodontitis. Dentures that are not cleaned regularly or properly can also harbor bacteria that cause halitosis.

Others Causes

  • Crash diets: Fasting and low-carbohydrate eating programs can produce halitosis. This is due to the breakdown of fats producing chemicals called ketones. These ketones have a strong aroma.
  • Drugs: Certain medications can reduce saliva and, therefore, increase odors. Other drugs can produce odors as they breakdown and release chemicals in the breath. Examples include nitrates used to treat angina, some chemotherapy chemicals, and some tranquilizers, such as phenothiazines. Individuals who take vitamin supplements in large doses can also be prone to bad breath.
  • Mouth, nose, and throat conditions: Sometimes, small, bacteria-covered stones can form on the tonsils at the back of the throat and produce odor. Also, infections or inflammation in the nose, throat, or sinuses can cause halitosis.
  • Foreign body: Bad breath can be caused if they have a foreign body lodged in their nasal cavity, especially in children.
  • Diseases: Some cancers, liver failure, and other metabolic diseases can cause halitosis, due to the specific mixes of chemicals that they produce. Gastroesophageal reflux (GERD) can cause bad breath due to the regular reflux of stomach acids.

Rarer Causes of Bad Breath

As mentioned earlier, the most common reason for bad breath is oral hygiene, but other situations can also be to blame.

Rarer causes of bad breath include:

  • Aspiration pneumonia: A swelling or infection in the lungs or airways due to inhaling vomit, saliva, food, or liquids.
  • Bowel obstruction: Breath can smell like feces if there has been a prolonged period of vomiting, especially if a bowel obstruction is present.
  • Bronchiectasis: This is a long-term condition in which airways become wider than normal, allowing for a build-up of mucus that leads to bad breath.
  • Ketoacidosis: When the insulin levels of a person with diabetes are very low, their bodies can no longer use sugar and begin to use fat stores instead. When fat is broken down, ketones are produced and build up. Ketones can be poisonous when found in large
  • Numbers and produce a distinctive and unpleasant breath odor. Ketoacidosis is a serious and potentially life-threatening condition.


Symptoms of Bad Breath

The specific odor of breath can vary depending on the cause of the problem. It is best to ask a close friend or relative to gauge your mouth odor, as it can be difficult to assess it yourself.

If no one is available, one way of checking the odor is to lick your wrist, leave it to dry, and then smell it. A bad smell on this area of the wrist is likely to suggest that you have halitosis.

Some individuals are concerned about their breath even though they may have little or no mouth odor. This condition is called halitophobia and can lead to obsessive mouth-cleansing behavior.

Diagnosis of Bad Breath

Often, a dentist will simply smell the breath of a person with suspected halitosis and rate the odor on a six-point intensity scale. The dentist may scrape the back of the tongue and smell the scrapings as this area can often be a source of the aroma.

There are a variety of sophisticated detectors that can rate odor more precisely.

They include the following:

  • Halimeter: This detects low levels of sulfur.
  • Gas chromatography: This test measures three volatile sulfur compounds: Hydrogen sulfide, methyl mercaptan, and dimethyl sulfide.
  • BANA test: This measures levels of a specific enzyme produced by halitosis-causing bacteria.
  • Beta-galactosidase test: Levels of the enzyme beta-galactosidase have been found to correlate with mouth odor.

The dentist will then be able to identify the likely cause of the bad breath.

Treatment of Bad Breath

The best method to reduce halitosis is good oral hygiene. This ensures that cavities are avoided and reduces the likelihood of gum disease.

It is recommended that individuals visit the dentist for a check-up and cleaning twice a year.

The dentist may recommend a toothpaste that includes an antibacterial agent or an antibacterial mouthwash.

Alternatively, if gum disease is present, professional cleaning may be necessary to clear out the build-up of bacteria in pockets between the gums and teeth.

Biospecimens

Bay Biosciences is a global leader in providing researchers with high quality, clinical grade, fully characterized human tissue samples, bio-specimens, and human bio-fluid collections.

Samples available include cancer (tumor) tissue, cancer serum, cancer plasma, cancer, peripheral blood mononuclear cells (PBMC). and human tissue samples from most other therapeutic areas and diseases.

Bay Biosciences maintains and manages its own biorepository, the human tissue bank (biobank) consisting of thousands of diseased samples (specimens) and from normal healthy donors available in all formats and types.

Our biobank procures and stores fully consented, deidentified and institutional review boards (IRB) approved human tissue samples and matched controls.

All our human tissue collections, human specimens and human bio-fluids are provided with detailed, samples associated patient’s clinical data.

This critical patient’s clinical data includes information relating to their past and current disease, treatment history, lifestyle choices, biomarkers, and genetic information.

Patient’s data is extremely valuable for researchers and is used to help identify new effective treatments (drug discovery & development) in oncology, and other therapeutic areas and diseases.

Bay Biosciences banks wide variety of human tissue samples and biological samples, including cryogenically preserved at – 80°C.

For example fresh frozen tissue samplestumor tissue samples, formalin-fixed paraffin-embedded (FFPE), tissue slides, with matching human bio-fluids, whole blood and blood-derived products such as serumplasma and PBMC.

Bay Biosciences is a global leader in collecting and providing human tissue samples according to the specified requirements and customized, tailor-made collection protocols.

Please contact us anytime to discuss your special research projects and customized human tissue sample requirements.

Types of Biospecimens

Bay Biosciences provides human tissue samples (human specimens) from diseased and normal healthy donors which includes:

Moreover, we can also procure most human bio-specimens, special collections and requests for human samples that are difficult to find. All our human tissue samples are procured through IRB-approved clinical protocols and procedures.

In addition to the standard processing protocols, Bay Biosciences can also provide human plasmaserum, and PBMC bio-fluid samples using custom processing protocols; you buy donor-specific collections in higher volumes and specified sample aliquots from us.

Bay Biosciences also provides human samples from normal healthy donors; volunteers, for controls and clinical research, contact us Now.

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