Bay Biosciences provides high quality, clinical grade bio-samples, sera (serum), plasma, peripheral blood mononuclear cells (PBMC) and bronchoalveolar lavage fluid (BAL) biofluid specimens from patients diagnosed with chronic obstructive pulmonary disease (COPD). Moreover, the serum, plasma and PBMCs are processed from patient’s peripheral whole-blood using customized processing protocols.

Furthermore, the sera (serum), plasma and PBMC bio-fluid are processed from chronic obstructive pulmonary disease (COPD) patient’s peripheral whole-blood using customized collection and processing protocols.

In addition, the samples are collected from unique patients diagnosed with chronic obstructive pulmonary disease (COPD) and are provided to a valued pharmaceutical customer for research, discovery and drug development.

 

Chronic Obstructive Pulmonary Disease (COPD) Overview

Chronic obstructive pulmonary disease (COPD) is, indeed, a primary, third leading cause of morbidity and mortality globally. Furthermore, COPD is the third leading cause of hospital readmissions in the United States.

Specifically, chronic obstructive pulmonary disease (COPD) is a group of progressive lung diseases. As a result, COPD can cause serious long-term disability and early death.

Emphysema

Notably, deaths resulting from COPD in women are higher than in men. Additionally, the most common of these diseases are emphysema and chronic bronchitis. In fact, most COPD patients have both of these conditions.

To elaborate, emphysema slowly destroys air sacs in the lungs, which, consequently, interferes with outward air flow. Specifically, emphysema causes shortness of breath. In patients with emphysema, the air sacs in the lungs (alveoli) are damaged.

Over time, therefore, the inner walls of the air sacs weaken and rupture, creating larger air spaces instead of many small ones. This, in turn, reduces the surface area of the lungs and, as a result, the amount of oxygen that reaches the bloodstream.

On the other hand, chronic bronchitis is characterized by inflammation and narrowing of the tubes that carry air to the lungs (bronchial tubes), which, in turn, allows mucus to build up and leads to a persistent cough.

Moreover, It’s estimated that about 30 million people in the United States have COPD. Furthermore, as many as half are unaware that they have it. Untreated, COPD can lead to a faster progression of disease, heart problems, and worsening respiratory infections.

Symptoms of COPD

Chronic obstructive pulmonary disease (COPD) makes it harder for patients to breathe. Symptoms may be mild at first, beginning with intermittent coughing and shortness of breath. As it progresses, symptoms can become more constant to where it can become increasingly difficult to breathe. COPD patients experience wheezing and tightness in the chest or have excess sputum production. Some patients with COPD have acute exacerbations, which are flare-ups of severe symptoms.

Signs and Symptoms of COPD

Many patients don’t recognize the symptoms of COPD until later stages of the disease. Sometimes patients think they are short of breath or less able to go about their normal activities because they are “just getting older.” Shortness of breath can be an important symptom of lung disease. Following are some of the common signs and symptoms of COPD:

Causes of COPD

Exact cause of COPD is unknown, following are the causes that contribute to COPD:

  • Smoking: Both current smoking and smoking in the past and exposure to second hand smoke is the main cause of COPD in men and women in the United States.
  • However, as many as 1 out of 4 Americans with COPD never smoked. Long-term exposure at home or work to air pollution, including secondhand smoke, chemical fumes and industrial dusts may cause COPD.
  • Respiratory infections may play a role in developing COPD.
  • A rare, inherited disorder called alpha-1-antitrypsin deficiency (AATD)

Biospecimens

biospecimens

Bay Biosciences is a global leader in providing researchers with high quality, clinical grade, fully characterized human tissue samples, bio-specimens, and human bio-fluid collections.

Moreover, human biospecimens are available including tumor tissue, serum, plasma and PBMC Samples from most other therapeutic areas.

Furthermore, Bay Biosciences maintains and manages its own biorepository, the human tissue bank (biobank) consisting of thousands of diseased samples (specimens) and likewise normal healthy donors for controls. Additionally, available in all formats and types.

In fact, our biobank procures and stores fully consented, de-identified and institutional review boards (IRB) approved human tissue samples, human biofluids such as serum samples, plasma samples from various diseases and matched controls.

Also, all our human tissue collections, human biospecimens and human biofluids are provided with detailed, samples associated patient’s clinical data.

In fact, this critical patient’s clinical data includes information relating to their past and current disease, treatment history, lifestyle choices, biomarkers, and genetic information.

Additionally, researchers find the patient’s data associated with the human biospecimens extremely valuable and use it to help identify new effective treatments (drug discovery & development) in oncology, as well as in other therapeutic areas and diseases.

Bay Biosciences banks wide variety of human tissue samples and human biological samples, including fresh frozen human biospecimens cryogenically preserved at – 80°C.

For example fresh frozen tissue samples, tumor tissue samples, formalin-fixed paraffin-embedded (FFPE), tissue slides, with matching human bio-fluids, whole blood and blood-derived products such as human serum, human plasma and human PBMCs.

Bay Biosciences is a global leader in collecting and providing human tissue samples according to the specified requirements and customized, tailor-made collection protocols.

Please contact us anytime to discuss your special research projects and customized human tissue sample requirements.

Types of Biospecimens

Bay Biosciences provides human tissue samples (human specimens) and human biofluids from diseased and normal healthy donors which includes:

Moreover, we can also procure most human biospecimens and human biofluids, special collections and requests for human samples that are difficult to find. All our human tissue samples and human biofluids are procured through IRB-approved clinical protocols and procedures.

In addition to the standard processing protocols, Bay Biosciences can also provide human biofluids such as  human plasma, human serum, and human PBMCs bio-fluid samples using custom processing protocols. you buy donor-specific collections in higher volumes and specified sample aliquots from us in multiple format and sets.

Bay Biosciences also provides human biospecimens from normal healthy donors; volunteers, for controls and clinical research, Contact us Now.