Bay Biosciences provides high quality, clinical grade, fresh frozen sera (serum), plasma and peripheral blood mononuclear cells (PBMC) biofluid samples from patients diagnosed with Coronary Artery Disease.

The sera (serum), plasma and PBMC biofluid specimens are processed from cerebral lupus patient’s peripheral whole-blood using customized collection and processing protocols. The coronary artery disease matched biofluid samples are collected from unique patients diagnosed with coronary artery disease and are provided to a valued pharmaceutical customer for research, diagnostics, discovery and drug development.

Detailed clinical data, patient’s history, symptoms, complete blood count (CBC), serology, MRI findings, histopathology information, elevated biomarker levels, genetic and metabolic information associated with coronary artery disease specimens is provided to a valued customer for research, development and drug discovery.

The coronary artery disease cancer sera (serum), plasma and peripheral blood mononuclear cells (PBMC) biofluids are processed from patients peripheral whole-blood using customized collection and processing protocols.

Coronary Artery Disease Overview

Coronary artery disease is the buildup of plaque in the arteries that supply oxygen-rich blood to the heart; more specifically, it is usually caused by the buildup of fatty material called plaque. Consequently, plaque causes a narrowing or blockage that could result in a heart attack. In addition, symptoms include chest pain or discomfort and shortness of breath.

Moreover, treatments include lifestyle changes and medications that target the risk factors and possibly surgery. Furthermore, coronary artery disease develops when the major blood vessels that supply the heart become damaged or diseased. Notably, cholesterol-containing deposits (plaques) in the coronary arteries and inflammation are usually to blame for coronary artery disease.

What are Coronary Arteries?

To elaborate, coronary arteries are the blood vessels that supply oxygen-rich blood to the heart muscle to keep it pumping. Indeed, the coronary arteries are directly on top of your heart muscle. Following this, here are the four main coronary arteries:

  • First, the right coronary artery.
  • Second, the left coronary artery.
  • Third, the left anterior descending artery.
  • Finally, the left circumflex artery.

As a result, because coronary artery disease often develops over decades, you might not notice a problem until you have a significant blockage or a heart attack. However, you can take steps to prevent and treat coronary artery disease. Ultimately, a healthy lifestyle can make a big impact.

Coronary Artery Disease

Coronary artery disease is caused by atherosclerosis. Specifically, atherosclerosis is the buildup of plaque inside your arteries. In fact, plaque consists of cholesterol, fatty substances, waste products, calcium, and the clot-making substance fibrin. Consequently, as plaque continues to collect on your artery walls, your arteries narrow and stiffen.

Moreover, plaque can clog or damage your arteries, which limits or stops blood flow to your heart muscle. If your heart does not get enough blood, it can’t get the oxygen and nutrients it needs to work properly. Therefore, this condition is called ischemia. Not getting enough blood supply to your heart muscle can lead to chest discomfort or chest pain, known as angina. Additionally, it also puts you at risk for a heart attack.

Signs and Symptoms of Coronary Artery Disease

Generally, patients don’t have any atherosclerosis symptoms until an artery is so narrowed or clogged that it cannot supply enough blood to the organs and tissues. Sometimes, a blood clot completely blocks blood flow, or even breaks apart, which can trigger a heart attack or stroke.

First, symptoms related to the clogged coronary arteries include:

  • Arrhythmia which is an abnormal heartbeat
  • Next, pain or pressure in your upper body, including your chest, arms, neck, or jaw. This is known as angina.
  • Shortness of breath

Second, Symptoms related to the arteries that deliver blood to the brain include:

  • First, numbness or weakness in the arms or legs
  • Next, a hard time speaking or understanding someone who’s talking
  • Moreover, drooping facial muscles
  • Furthermore, paralysis
  • Likewise, severe headache
  • Finally, problems with vision in one or both eyes

Next, symptoms related to the arteries of your arms, legs, and pelvis include:

  • Pain in the legs when walking
  • Numbness

Lastly, symptoms related to the arteries that deliver blood to the kidneys include:

Biospecimens

biospecimens

Bay Biosciences is a global leader in providing researchers with high quality, clinical grade, fully characterized human tissue samples, bio-specimens, and human bio-fluid collections.

Moreover, human biospecimens are available including tumor tissue, serum, plasma and PBMC samples from most other therapeutic areas.

Furthermore, Bay Biosciences maintains and manages its own biorepository, the human tissue bank (biobank) consisting of thousands of diseased samples (specimens) and likewise normal healthy donors for controls. Additionally, available in all formats and types.

In fact, our biobank procures and stores fully consented, de-identified and institutional review boards (IRB) approved human tissue samples, human biofluids such as serum samples, plasma samples from various diseases and matched controls.

Also, all our human tissue collections, human biospecimens and human biofluids are provided with detailed, samples associated patient’s clinical data.

In fact, this critical patient’s clinical data includes information relating to their past and current disease, treatment history, lifestyle choices, biomarkers, and genetic information.

Additionally, researchers find the patient’s data associated with the human biospecimens extremely valuable and use it to help identify new effective treatments (drug discovery & development) in oncology, as well as in other therapeutic areas and diseases.

Bay Biosciences banks wide variety of human tissue samples and human biological samples, including fresh frozen human biospecimens cryogenically preserved at – 80°C.

For example fresh frozen tissue samples, tumor tissue samples, formalin-fixed paraffin-embedded (FFPE), tissue slides, with matching human bio-fluids, whole blood and blood-derived products such as human serum, human plasma and human PBMCs.

Bay Biosciences is a global leader in collecting and providing human tissue samples according to the specified requirements and customized, tailor-made collection protocols.

Please contact us anytime to discuss your special research projects and customized human tissue sample requirements.

Types of Biospecimens

Bay Biosciences provides human tissue samples (human specimens) and human biofluids from diseased and normal healthy donors which includes:

Moreover, we can also procure most human biospecimens and human biofluids, special collections and requests for human samples that are difficult to find. All our human tissue samples and human biofluids are procured through IRB-approved clinical protocols and procedures.

In addition to the standard processing protocols, Bay Biosciences can also provide human biofluids such as  human plasma, human serum, and human PBMCs bio-fluid samples using custom processing protocols; you buy donor-specific collections in higher volumes and specified sample aliquots from us.

Bay Biosciences also provides human biospecimens from normal healthy donors; volunteers, for controls and clinical research, Contact us Now.