Lung Cancer Tumor Tissue Samples for Research
Bay Biosciences provides high quality, clinical grade lung cancer formalin fixed paraffin embedded (FFPE) tumor tissue samples, along with matching serum and plasma bio-fluid specimens, from unique patients diagnosed with lung cancer.
Moreover, the NSCLC tumor tissue samples with matched serum and plasma include detailed patient information and clinical data
Types of Lung Cancers
Lung cancers are divided into the following two main types:
1). Non-Small Cell Lung Cancer (NSCLC)
2). Small-Cell Lung Cancer (SCLC)
Non-Small Cell Lung Cancer
Majority of the lung cancer (NSCLC) cases in the United States, around 85%, are Non-small Cell Lung cancer (NSCLC). Specifically, the main subtypes of NSCLC are adenocarcinoma, squamous cell carcinoma, and large cell carcinoma.
Moreover, these subtypes, which start from different types of lung cells, are grouped together as NSCLC.
Types of Non-Small Cell Lung Cancer
Following are the types of Non-small cell lung cancer (NSCLC):
Lung adenocarcinomas start in the glandular cells that normally secrete substances such as mucus. Furthermore, they tend to develop in smaller airways, such as alveoli.
In addition, lung cancers occur mainly in patients who are current or former smokers.
However, it also represents the most common type of lung cancer seen in non-smokers.
Moreover, it affects more women than men, and younger people are more likely to develop it.
Doctors mostly find adenocarcinoma in the outer edges of the lung, and it tends to grow slower than other lung cancers.
Consequently, this usually allows for earlier detection before it spreads to other organs and parts of the body.
Patients with a type of called adenocarcinoma in situ tend to have a better outlook than those with other types of lung cancer.
On the other hand, squamous cell carcinomas start in flat cells that line the inside of the airways in the lungs, which are called squamous cells.
Additionally, doctors usually link squamous cell carcinomas to patients who have a history of smoking. They mostly find squamous cell carcinomas in the central part of the lungs, near a main airway (bronchus).
Large cell carcinoma can develop in any part of the lung. Furthermore, it tends to grow and spread quickly, which can make treatment harder. In addition, a subtype of large cell carcinoma, known as large cell neuroendocrine carcinoma, represents a fast-growing cancer that is very similar to small cell lung cancer.
Moreover, a few other subtypes of non-small cell lung cancer (NSCLC), such as adenosquamous carcinoma and sarcomatoid carcinoma, are rare and not as common as adenocarcinomas or squamous cell carcinomas.
Small Cell Lung Cancer (SCLC)
Around 20% of lung cancers diagnosed in the United States are, notably, doctors finding small cell lung cancer (SCLC). Furthermore, doctors consider small-cell lung cancer a more aggressive form of lung cancer, as it tends to grow quickly and, in addition, spread faster than Non-small SCLC to other organs and parts of the body, thereby metastasizing more easily.
Consequently, about 70% of patients with SCLC will have cancer that has already spread by the time doctors diagnose them. Since this cancer grows quickly, it tends to respond well to chemotherapy and radiation therapy.
Unfortunately, for most patients, the SCLC cancer will return at some point; thus, long-term survival is not common. Moreover, medical professionals may also refer to small cell lung cancer as oat cell cancer, oat cell carcinoma, and small cell undifferentiated carcinoma.
Biospecimens
Bay Biosciences is, indeed a global leader in providing researchers with high quality, clinical grade, fully characterized human tissue samples, bio-specimens, and human bio-fluid collections.
Specifically, aamples available include cancer (tumor) tissue, cancer serum, cancer plasma, cancer, peripheral blood mononuclear cells (PBMC). and human tissue samples from most other therapeutic areas and diseases.
Moreover, Bay Biosciences maintains and manages its own biorepository, the human tissue bank (biobank) consisting of thousands of diseased samples (specimens) and from normal healthy donors available in all formats and types.
In fact, our biobank procures and stores fully consented, de-identified and institutional review boards (IRB) approved human tissue samples and matched controls.
Additionally, all our human tissue collections, human specimens and human bio-fluids are provided with detailed, samples associated patient’s clinical data.
In particular, critical patient’s clinical data includes information relating to their past and current disease, treatment history, lifestyle choices, biomarkers, and genetic information.
Moreover, patient’s data is extremely valuable for researchers and is used to help identify new effective treatments (drug discovery & development) in oncology, and other therapeutic areas and diseases.
Specifically, Bay Biosciences banks wide variety of human tissue samples and biological samples, including cryogenically preserved at – 80°C.
For example fresh frozen tissue samples, tumor tissue samples, formalin-fixed paraffin-embedded (FFPE), tissue slides, with matching human bio-fluids, whole blood and blood-derived products such as serum, plasma and PBMC.
Furthermore, Bay Biosciences is a global leader in collecting and providing human tissue samples according to the specified requirements and customized, tailor-made collection protocols.
Therefore, please contact us anytime to discuss your special research projects and customized human tissue sample requirements.
Types of Biospecimens
Bay Biosciences provides human tissue samples (human specimens) from diseased and normal healthy donors which includes:
- Peripheral whole-blood
- Amniotic fluid
- Bronchoalveolar lavage fluid (BAL)
- Sputum
- Pleural effusion
- Cerebrospinal fluid (CSF)
- Serum (sera)
- Plasma
- Peripheral blood mononuclear cells (PBMC)
- Saliva
- Buffy coat
- Urine
- Stool samples
- Aqueous humor
- Vitreous humor
- Kidney stones (renal calculi)
- Other bodily fluids from most diseases including cancer.
Customized Collections
Moreover, we can also procure most human bio-specimens, furthermore; we offer special collections and requests for human samples that are difficult to find. All our human tissue samples are procured through IRB-approved clinical protocols and procedures.
In addition to the standard processing protocols, Bay Biosciences can also provide human plasma, serum, and PBMC bio-fluid samples using custom processing protocols. Additionally you buy donor-specific collections in higher volumes and specified sample aliquots from us.
Furthermore, Bay Biosciences also provides human samples from normal healthy donors; volunteers, for controls and clinical research, contact us Now.
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