Bay Biosciences provides high quality, clinical grade lung cancer formalin fixed paraffin embedded (FFPE) tumor tissue samples, with matching serum and plasma biofluid specimens, from unique patients diagnosed with squamous cell carcinoma, adenocarcinoma and large cell carcinoma Non-small Cell Lung cancer (NSCLC). The NSCLC tumor tissue samples with matched serum and plasma are provided with detailed patient information and clinical data to a pharmaceutical customer for research, development and drug discovery.
Types of Lung Cancers
Lung cancers are classified into the following two main types:
Non-Small Cell Lung Cancer (NSCLC)
Small-Cell Lung Cancer (SCLC)
Non-Small Cell Lung Cancer
Majority of the lung cancer (NSCLC) cases in the United States, around 85% are Non-small Cell Lung cancers (NSCLC). The main subtypes of NSCLC are adenocarcinoma, squamous cell carcinoma, and large cell carcinoma. These subtypes, which start from different types of lung cells are grouped together as NSCLC because their treatment and prognoses (outlook) are often similar.
Types of Non-Small Cell Lung Cancer
Following are the sub-types of Non-small cell lung cancer (NSCLC):
Adenocarcinoma: Lung Adenocarcinomas start in the glandular cells that normally secrete substances such as mucus and tends to develop in smaller airways, such as alveoli. Lung Adenocarcinoma cancers occurs mainly in patients who are current or former smokers, but it is also the most common type of lung cancer seen in non-smokers. It is more common in women than in men, and it is more likely to occur in younger people than other types of lung cancer. Adenocarcinoma is mostly found in the outer edges of the lung, it tends to grow slowly than other lung cancer, and is usually likely to be detected before it has spread to other organs and parts of the body. Patients with a type of adenocarcinoma called adenocarcinoma in situ (previously called bronchioloalveolar carcinoma) tend to have a better outlook than those with other types of lung cancer.
Squamous Cell Carcinoma: Squamous cell carcinomas is a lung cancer which starts in flat cells that line the inside of the airways in the lungs, which are called squamous cells. Squamous cell carcinomas are usually linked to patients who have a history of smoking. Squamous cell carcinomas are mostly found in the central part of the lungs, near a main airway (bronchus).
Large Cell (undifferentiated) Carcinoma: Large cell carcinoma can develop in any part of the lung. It tends to grow and spread quickly, which can make it harder to treat. A subtype of large cell carcinoma, known as large cell neuroendocrine carcinoma, is a fast-growing cancer that is very similar to small cell lung cancer.
Other subtypes: There are few other subtypes of Non-small cell lung cancer (NSCLC), such as adenosquamous carcinoma and sarcomatoid carcinoma, are rare and not as common as adenocarcinomas or squamous cell carcinomas.
Small Cell Lung Cancer (SCLC)
Around 20% of lung cancers diagnosed in the United States are found to be small cell lung cancer (SCLC).
Small-cell lung cancer is more aggressive form of lung cancer, it tends to grow quickly and spread faster than Non-small SCLC to other organs and parts of the body, metastasize more easily. About 70% of patients with SCLC will have cancer that has already spread at the time they are diagnosed. Since this cancer grows quickly, it tends to respond well to chemotherapy and radiation therapy. Unfortunately, for most patients, the SCLC cancer will return at some point and long term survival is not common. Small cell lung cancer may also be referred to as oat cell cancer, oat cell carcinoma, and small cell undifferentiated carcinoma.
Bay Biosciences is a global leader in providing researchers with high quality, clinical grade, fully characterized human tissue samples, bio-specimens and human bio-fluid collections from cancer (tumor) tissue, cancer–serum, cancer–plasma cancer-PBMC and human tissue samples from most other therapeutic areas and diseases.
Bay Biosciences maintains and manages it’s own bio-repository, human tissue bank (biobank) consisting of thousands of diseased samples (specimens) and from normal healthy donors available in all formats and types. Our biobank procures and stores fully consented, deidentified and institutional review boards (IRB) approved human tissue samples and matched controls.
All our human human tissue collections, human specimens and human bio-fluids are provided with detailed samples associated patient’s clinical data. This critical patient’s clinical data includes information relating to their past and current disease, treatment history, lifestyle choices, biomarkers and genetic information. Patient’s data is extremely valuable for researchers and is used to help identify new effective treatments (drug discovery & development) in oncology, other therapeutic areas and diseases. This clinical information is critical to demonstrate their impact, monitor the safety of medicines, testing & diagnostics, and generate new knowledge about the causes of disease and illness.
Bay Biosciences banks wide variety of human tissue samples and biological samples including cryogenically preserved -80°C, fresh, fresh frozen tissue samples, tumor tissue samples, FFPE’s, tissue slides, with matching human bio-fluids, whole blood and blood derived products such as serum (sera), plasma and PBMC’s.
Bay Biosciences is a global leader in collecting and providing human tissue samples according to the researchers specified requirements and customized, tailor made collection protocols. Please contact us anytime to discuss your special research projects and customized human tissue sample requirements.
Bay Biosciences provides human tissue samples (human specimens) from diseased and normal healthy donors; including peripheral whole-blood, amniotic fluid, bronchoalveolar lavage fluid (BAL), sputum, pleural effusion, cerebrospinal fluid (CSF), serum (sera), plasma, peripheral blood mononuclear cells (PBMC’s), saliva, Buffy coat, urine, stool samples, aqueous humor, vitreous humor, kidney stones, renal calculi, nephrolithiasis, urolithiasis and other bodily fluids from most diseases including cancer. We can also procure most human bio-specimens and can do special collections and requests of human samples that are difficult to find. All our human tissue samples are procured through IRB approved clinical protocols and procedures.
In addition to the standard processing protocols Bay Biosciences can also provide human plasma, serum, PBMC bio-fluid samples using custom processing protocols, you can buy donor specific sample collections in higher volumes and specified sample aliquoting from us. Bay Biosciences also provides human samples from normal healthy donors, volunteers, for controls and clinical research, contact us Now.
日本のお客様は、ベイバイオサイエンスジャパンBay Biosciences Japanまたはhttp://baybiosciences-jp.com/contact/までご連絡ください。