Bay Biosciences provides high quality, clinical grade, biopsy tumor tissue samples, FFPE tumor tissue blocks with matched cryogenically preserved sera (serum), plasma, peripheral blood mononuclear cells (PBMC) biofluid samples from patients diagnosed with mantle cell lymphoma.
The sera (serum), plasma and PBMC biofluid specimens are processed from mantle cell lymphoma patient’s peripheral whole-blood using customized collection and processing protocols. The mantle cell lymphoma biopsy tumor tissue and matched biofluid samples are collected from unique patients diagnosed with mantle cell lymphoma and are provided to a valued pharmaceutical customer for research, diagnostics, discovery and drug development.
Detailed clinical data, patient’s history, symptoms, complete blood count (CBC), serology, MRI, biopsy tumor tissue findings, histopathology information, elevated biomarker levels, genetic and metabolic information associated with mantle cell lymphoma specimens is provided to a valued customer for research, development and drug discovery.
The mantle cell lymphoma sera (serum), plasma and peripheral blood mononuclear cells (PBMC) biofluids are processed from patients peripheral whole-blood using customized collection and processing protocols.
Mantle Cell Lymphoma (MCL) Overview
Mantle cell lymphoma (MCL) is a type of non-Hodgkin’s lymphoma, which is a form of cancer that affects the lymphatic system. Lymphomas are cancers that involve white blood cells, and can be divided depending on the type of cell involved, either B-lymphocytes or T-lymphocytes. Mantle cell lymphoma (MCL) is a B-cell lymphoma that develops from malignant B-lymphocytes within a region of the lymph node known as the mantle zone. It affects mostly men who are usually 60 to 70 years old. Mantle Cell lymphoma is typically an aggressive, rare, form of non-Hodgkin’s lymphoma (NHL) that arises from cells originating in the “mantle zone.” Mantle cell lymphoma (MCL) accounts for roughly six percent of all NHL cases in the United States.
Mantle cell lymphoma (MCL) is mostly diagnosed at a later stage of disease and in most cases involves the gastrointestinal tract and bone marrow. Overproduction of a protein that helps control cell division called cyclin D1 in the lymphoma cells is found in more than 90 percent of patients with mantle cell lymphoma (MCL). Identification of excess cyclin D1 from a biopsy is considered a very sensitive tool for diagnosing mantle cell lymphoma (MCL). One-quarter to one-half of patients with mantle cell lymphoma (MCL) also have higher-than-normal levels of certain proteins that circulate in the blood, such as lactate dehydrogenase (LDH) and beta-2 microglobulin. Measuring these and other proteins can help doctors determine how aggressive the disease is and may help decide on effective treatment.
Bay Biosciences is a global leader in providing researchers with high quality, clinical grade, fully characterized human tissue samples, bio-specimens and human bio-fluid collections from cancer (tumor) tissue, cancer serum, cancer plasma cancer PBMC and human tissue samples from most other therapeutic areas and diseases.
Bay Biosciences maintains and manages it’s own bio-repository, human tissue bank (biobank) consisting of thousands of diseased samples (specimens) and from normal healthy donors available in all formats and types. Our biobank procures and stores fully consented, deidentified and institutional review boards (IRB) approved human tissue samples and matched controls.
All our human human tissue collections, human specimens and human bio-fluids are provided with detailed samples associated patient’s clinical data. This critical patient’s clinical data includes information relating to their past and current disease, treatment history, lifestyle choices, biomarkers and genetic information. Patient’s data is extremely valuable for researchers and is used to help identify new effective treatments (drug discovery & development) in oncology, other therapeutic areas and diseases. This clinical information is critical to demonstrate their impact, monitor the safety of medicines, testing & diagnostics, and generate new knowledge about the causes of disease and illness.
Bay Biosciences banks wide variety of human tissue samples and biological samples including cryogenically preserved -80°C, fresh, fresh frozen tissue samples, tumor tissue samples, FFPE’s, tissue slides, with matching human bio-fluids, whole blood and blood derived products such as serum, plasma and PBMC’s.
Bay Biosciences is a global leader in collecting and providing human tissue samples according to the researchers specified requirements and customized, tailor made collection protocols. Please contact us anytime to discuss your special research projects and customized human tissue sample requirements.
Bay Biosciences provides human tissue samples (human specimens) from diseased and normal healthy donors; including peripheral whole-blood, amniotic fluid, bronchoalveolar lavage fluid (BAL), sputum, pleural effusion, cerebrospinal fluid (CSF), serum (sera), plasma, peripheral blood mononuclear cells (PBMC’s), saliva, Buffy coat, urine, stool samples, aqueous humor, vitreous humor, kidney stones, renal calculi, nephrolithiasis, urolithiasis and other bodily fluids from most diseases including cancer. We can also procure most human bio-specimens and can do special collections and requests of human samples that are difficult to find. All our human tissue samples are procured through IRB approved clinical protocols and procedures.
In addition to the standard processing protocols Bay Biosciences can also provide human plasma, serum, PBMC bio-fluid samples using custom processing protocols, you can buy donor specific sample collections in higher volumes and specified sample aliquoting from us. Bay Biosciences also provides human samples from normal healthy donors, volunteers, for controls and clinical research, contact us Now.
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