Bay Biosciences provides high quality, clinical grade samples with matched frozen sera (serum), K2-EDTA plasma and PBMC samples from unique peripheral neuropathy patients.
The sera (serum), K2-EDTA plasma and PBMCs are processed from peripheral neuropathy patient’s peripheral whole-blood using customized collection and processing protocols.
Peripheral Neuropathy Overview
Treatments include rest, hot compresses, or taking a limited course of drugs to reduce inflammation.
Peripheral neuropathy is a general term that describes many conditions caused by damage to the peripheral nervous system.
The peripheral nerves are any nerves located outside the spinal cord and brain. They send sensory messages to the central nervous system (CNS) and receive messages from the spinal cord and brain to move muscles throughout the body.
Peripheral neuropathy can cause a loss of normal nerve signals or cause inappropriate or distorted signals. It affects millions of people in the United States.
The condition can affect various nerves and impact the body in different ways. It can affect a single nerve or several nerves at the same time.
Examples of peripheral neuropathy include:
- Bell’s palsy, which is a single-nerve neuropathy that affects the face.
- Carpal tunnel syndrome, which occurs due to compression of the nerves in the wrist.
- Diabetic or alcohol-related neuropathy, which can cause sensory loss and pain in the hands and feet.
- Postherpetic neuralgia, which can follow shingles and last for many months after the rash disappears
- Peroneal nerve palsy, which is due to compression of the fibular nerve in the leg.
- Ulnar nerve palsy, such as after an injury to the elbow.
Examples of Peripheral Neuropathy
Examples of peripheral neuropathy include the following:
- Postherapetic neuralgia, which can follow shingles and last for many months after the rash disappears
- Ulnar nerve palsy, such as after an injury to the elbow.
- Carpal tunnel syndrome, which occurs due to compression of the nerves in the wrist.
- Peroneal nerve palsy, which is due to compression of the fibular nerve in the leg.
- Bells palsy, which is a single-nerve neuropathy that affects the face.
- Diabetic or alcohol-related neuropathy, which can cause sensory loss and pain in the hands and feet.
Symptoms of Peripheral Neuropathy
General symptoms of peripheral neuropathy include:
However, symptoms of peripheral neuropathy may vary according to the type of neuropathy.
Researchers have identified more than 100 different types of neuropathy.
Types of Peripheral Neuropathy
Generally, experts classify the types into three categories, each with its own specific symptoms.
Sensory neuropathy
This affects the sensory nerves, which impact the sensations of pain, touch, and temperature.
The person may have:
- Decreased sensation of vibration and touch
- Burning, stabbing, lancing, or shooting pains, which may worsen at night
- Increased pain or inability to feel pain
- Inability to detect changes in heat and cold
- Difficulty with coordination and balance
- Pins and needles and hypersensitivity
Motor Neuropathy
This affects the muscles that the brain controls consciously.
Symptoms include:
- Muscle weakness, leading to instability and difficulty performing small movements, such as buttoning a shirt
- Twitching of muscle and and cramps
- Shrinking of muscle
Autonomic Neuropathy
This affects body processes that the brain controls involuntarily. Symptoms may include:
- Abnormal sweat responses
- Problems with bowel or bladder control
- Heat intolerance
- Problems with blood pressure
- Dysregulated body temperature
- Problems with swallowing dysphagia
Summary
Vitamins are essential nutrients that mainly come from foods. Each performs various roles in the body, and deficiencies of different vitamins can harm health in different ways.
Aim to get vitamins from a balanced, varied diet that contains plenty of fruits and vegetables. If a person is pregnant or has a health issue or a restricted diet, a doctor or nutritionist may recommend supplements.
Biospecimens
Bay Biosciences is a global leader in providing researchers with high quality, clinical grade, fully characterized human tissue samples, bio-specimens, and human bio-fluid collections.
Samples available include cancer (tumor) tissue, cancer serum, cancer plasma, cancer, peripheral blood mononuclear cells (PBMC). and human tissue samples from most other therapeutic areas and diseases.
Bay Biosciences maintains and manages its own bio-repository, the human tissue bank (biobank) consisting of thousands of diseased samples (specimens) and from normal healthy donors available in all formats and types.
In fact, our biobank procures and stores fully consented, de-identified and institutional review boards (IRB) approved human tissue samples and matched controls.
Our human tissue collections, specimens, and bio-fluids come with detailed patient clinical data associated with them.
So this critical patient’s clinical data includes information relating to their past and current disease, treatment history, lifestyle choices, biomarkers, and genetic information.
Additionally, new effective treatments (drug discovery & development) in oncology, and other therapeutic areas and diseases are identified by researchers using patient’s data which is extremely valuable.
Bay Biosciences banks wide variety of human tissue samples and biological samples, including cryogenically preserved at – 80°C.
For example fresh frozen tissue samples, tumor tissue samples, formalin-fixed paraffin-embedded (FFPE), tissue slides, with matching human bio-fluids, whole blood and blood-derived products such as serum, plasma and PBMC.
Bay Biosciences is a global leader in collecting and providing human tissue samples according to the specified requirements and customized, tailor-made collection protocols.
Please contact us anytime to discuss your special research projects and customized human tissue sample requirements.
Types of Biospecimens
Bay Biosciences provides human tissue samples (human specimens) from diseased and normal healthy donors which includes:
- Peripheral whole-blood
- Amniotic fluid
- Bronchoalveolar lavage fluid (BAL)
- Sputum
- Pleural effusion
- Cerebrospinal fluid (CSF)
- Serum (sera)
- Plasma
- Peripheral blood mononuclear cells (PBMC)
- Saliva
- Buffy coat
- Urine
- Stool samples
- Aqueous humor
- Vitreous humor
- Kidney stones (renal calculi)
- Other bodily fluids from most diseases including cancer.
Moreover, we can also procure most human bio-specimens, special collections and requests for human samples that are difficult to find. All our human tissue samples are procured through IRB-approved clinical protocols and procedures.
In addition to the standard processing protocols, Bay Biosciences can also provide human plasma, serum, and PBMC bio-fluid samples using custom processing protocols; you buy donor-specific collections in higher volumes and specified sample aliquots from us.
Bay Biosciences also provides human samples from normal healthy donors; volunteers, for controls and clinical research, contact us Now.
日本のお客様は、ベイバイオサイエンスジャパンBay Biosciences Japanまたはhttp://baybiosciences-jp.com/contact/までご連絡ください。