What is Paralysis?
What is Paralysis?
Paralysis is the loss of voluntary muscle function in one or more parts of the body because of damage to the nervous system.
The nervous system has two parts:
- First, the central nervous system (CNS), which includes the brain and spinal cord.
- Second, the peripheral nervous system (PNS), which contains the nerves outside of the CNS.
Moreover, the nerve cells, or neurons, in the PNS serve several functions.
For instance, motor neurons regulate muscle movement. On the other hand, sensory neurons send information about pressure, pain, and temperature, for example to the CNS.
Consequently, paralysis occurs when nerve signals are interrupted because of damage to the nerves or spinal cord.
Types of Paralysis
In addition, doctors classify paralysis based on the following characteristics:
Severity
In particular, the degree of muscle function loss determines the severity of paralysis.
For example, partial paralysis, or paresis, causes significant muscle weakness and impaired movement. However, people with paresis retain a small degree of control over the affected muscles.
In contrast, complete paralysis occurs when a person cannot move the affected body part.
Duration
Duration refers to how long the paralysis lasts.
Firstly, some medical conditions, such as sleep paralysis, stroke, and Bell’s palsy, can cause temporary paralysis. Over time, however, people can regain partial or complete control over the affected muscles.
In addition, other conditions that can cause the problem temporarily include hyperkalemic or hypokalemic periodic paralysis. These conditions occur as a result of mutations that affect the CACNA1S or SCN4A genes.
Furthermore, these genes carry instructions for making proteins that transport sodium and calcium ions into and out of muscle cells. Consequently, the flow of ions within muscle cells helps produce muscle contractions and movement.
Moreover, disruptions in the ion flow can lead to periodic episodes of muscle weakness and paralysis.
Meanwhile, severe head or neck injuries and neuromuscular disorders can lead to permanent paralysis.
Location
Localized paralysis affects a small area of the body, such as the face, hands, or feet.
Generalized paralysis affects a larger area, including multiple parts of the body.
Types of paralysis include:
- Monoplegia: This affects one area, such as one arm or leg.
- Hemiplegia: This affects one arm and one leg on the same side of the body.
- Paraplegia: Also called lower body paralysis, this affects both legs and sometimes the hips and organs in the lower abdomen.
- Quadriplegia: This affects both arms and legs, and sometimes muscles in the trunk, the functions of internal organs, or both.
Damage to the spinal cord is the most common cause of paraplegia.
Muscle Tension
Flaccid paralysis, on the other hand, damages the lower motor neurons that stimulate skeletal muscle movement. Consequently, over time, the muscles shrink or deteriorate.
Flaccid paralysis is, in fact, a common complication of polio, according to the Centers for Disease Control and Prevention (CDC)Trusted Source.
Moreover, other causes include inflammation of the spinal cord, also called myelitis, and Guillain-Barré syndrome, which is a rareTrusted Source autoimmune disorder in which the immune system attacks the PNS.
In contrast, spastic paralysis causes muscle stiffness, involuntary spasms, and muscle weakness. This form of paralysis can result from spinal cord injuries, amyotrophic lateral sclerosis (ALS), stroke, or hereditary spastic paraplegia.
Symptoms
Furthermore, symptoms vary, depending on the type and cause of the issue. Specifically, the most common paralysis symptom is the loss of muscle function in one or more parts of the body.
Additionally, other symptoms that may accompany paralysis include:
- First, involuntary spasms or twitches
- Second, muscle weakness
- Next, numbness or pain in the affected muscles
- Likewise, stiffness
- Finally, visible signs of muscle loss (muscle atrophy)
Causes
According to the results of the 2013 U.S. Paralysis Prevalence and Health Disparities Survey, the most common causes of paralysis in the United States include:
- Specifically, stroke
- Moreover, spinal cord injury
- Furthermore, cerebral palsy
- Finally, multiple sclerosis (MS)
Furthermore, muscle weakness and paralysis result from damage to the nervous system, which notably any of the health problems above can cause.
In general, a healthy nervous system sends information back and forth between the brain and the rest of the body. Consequently, signals from the brain travel down the spinal cord and into the peripheral nerves throughout the body.
Moreover, the peripheral nerves regulate numerous functions, including:
- For instance, automatic functions, such as breathing and digestion
- Also, voluntary muscle movements, such as walking and chewing
- Additionally, sensory functions, such as pain, temperature, and pressure detection
As a result, damage to any part of the nervous system can have severe effects on a person’s overall health and quality of life.
Additionally, some other possible causes of nervous system damage and resulting muscle weakness or paralysis include:
- For example, brain or spinal cord tumors
- Next, infections infections, such as meningitis, encephalitis, and polio
- Moreover, spina bifida, or the incomplete development of the brain, spine, or spinal cord
- Furthermore, motor neuron diseases, such as ALS and primary lateral sclerosis
- Also, autoimmune diseases, including Guillain-Barre syndrome and lupus
Lastly, inherited disorders, including spinal muscular atrophy and hypo- or hyperkalemic partial paralysis
Tick Paralysis
Treatment
Regarding Treatment, currently, no cure for paralysis exists. Nevertheless, depending on the cause and type of the issue, some people experience partial or complete recovery.
For instance, temporary paralysis, such as that caused by Bell’s palsy or stroke, may resolve on its own without medical treatment.
Additionally, when paralysis results from a spinal cord injury or chronic neurological condition, a person may recover partial muscle control.
Although rehabilitation does not cure paralysis completely, it can help prevent symptoms from worsening.
Moreover, available treatments include:
- Firstly, physical therapy
- Secondly, occupational therapy
- Thirdly, mobility devices, such as braces, walkers, and wheelchairs
- Moreover, medications
- Furthermore, surgical amputation
- Finally, nerve transfer surgery
Finally, emotional and social support can also play vital roles in a person’s treatment.
Summary
Paralysis is the temporary or permanent loss of movement in one or more parts of the body.
Many people with paralysis, unfortunately, do not regain full mobility or sensation in the affected area. However, physical therapy, mobility devices, and social and emotional support can, in fact, help improve the quality of life.
Additionally, medication and surgery can often help, as well. Therefore, a doctor will base treatment recommendations on the severity and, importantly, the underlying cause of a person’s paralysis.
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Types of Biospecimens
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Moreover, we can also procure most human bio-specimens, furthermore; we offer special collections and requests for human samples that are difficult to find. All our human tissue samples are procured through IRB-approved clinical protocols and procedures.
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