Bay Biosciences provides FFPE tumor tissue blocks, normal adjacent tissue bio-specimens, with matched sera (serum), plasma, peripheral blood mononuclear cells (PBMC) and bronchoalveolar lavage fluid (BAL) samples from patients diagnosed with squamous cell carcinoma (SCC), non-small cell lung carcinoma (NSCLC).

Moreover, the serum,, plasma and PBMCs are processed from NSCLC-SCC patient’s peripheral whole-blood using customized collection and processing protocols.  

Furthermore, the biopsy tumor tissue, normal adjacent tissue and matched biofluid samples are collected from unique patients diagnosed with stage III and IV non-small cell lung carcinoma NSCLC-SCC and are provided to a valued pharmaceutical customer for research, diagnostics, discovery and drug development.

In addition, detailed clinical data, lung squamous cell carcinoma (SCC) patient’s history, symptoms, complete blood count (CBC), serology, MRI, biopsy tumor tissue, histopathology information, elevated biomarker levels, genetic and metabolic information associated with SCC specimens is provided to a valued customer for research, development and drug discovery.

The squamous cell carcinoma (SCC) sera (serum), plasma and peripheral blood mononuclear cells (PBMC) biofluids are processed from patients peripheral whole-blood using customized collection and processing protocols.

Adenocarcinoma Overview

In fact, adenocarcinoma is a type of cancer that forms in the glands in the body that secrete mucus. Moreover, adenocarcinoma can develop in many different organs or parts of the body, including the colon, breasts, prostate, pancreas, esophagus, or lungs

. Furthermore, adenocarcinoma is a common type of some of these cancers. For example, the majority of all prostate cancers (99%) and most of the pancreatic cancers (85%) are adenocarcinomas.

Additionally, adenocarcinoma develops when the cells in the glands that line the organs begin to grow out of control. Consequently, these cells can harm healthy tissues in your body and start spreading to other parts of your body.

Adenocarcinoma of the Lung Overview

Notably, adenocarcinoma is the most common form of lung cancer. Specifically, about 40 percent of all lung cancers are adenocarcinomas. While adenocarcinomas associate with smoking and tobacco use, it is important to note that these cancers are also the most common form in patients who have never smoked cigarettes before, especially in women who have never smoked in their life.

Furthermore, adenocarcinoma is a type of non-small cell lung cancer (NSCLC). Typically, it begins in the outer edges of the lungs and the lining of the bronchi, which are the airway passages into the lungs.”

Adenocarcinoma grows more slowly than other types of lung cancer and forms smaller masses, but it can also metastasize in its early stages.

Signs and Symptoms of Adenocarcinoma of the Lung

Following are the common signs and symptoms of adenocarcinoma of the lung:
  • Problems with breathing
  • Persistent cough that does not go away and gets worse
  • Coughing up blood
  • Chest pain, which gets worse by deep breathing, coughing or laughing 
  • Feeling tired or weak
  • Fatigue
  • Loss of appetite
  • Hoarseness in voice when talking
  • Recurring lung infections, like bronchitis or pneumonia
  • Wheezing without history of asthma
  • Unexplained weight loss

Adenocarcinoma of the Lung Diagnosis

Patients who have the symptoms of lung cancer, will be asked to get several imaging and lab tests done. Following are some of the tests used for the diagnosis of adenocarcinoma of the lung:

  • A chest x-ray, which could show masses in the lungs that may be caused by cancer
  • CT scans, which can show lung cancer and cancer that may have metastasized (spread) to other parts of the body
  • Testing the sputum (coughed-up mucus)
  • Examining the lungs with a lighted tube (bronchoscopy)
  • Biopsy, which involves taking a piece of tissue and testing it for cancerous cells

Once the adenocarcinoma is detected from the above test results, the next step will be to try to find out how advanced the cancer is and whether it has metastasized or spread beyond the lungs. This is called the stage of cancer. The stages of lung cancer range from 0 to IV, with the lower stages indicating cancer that is limited to the lung, and stage IV indicating the cancer has spread to other locations and organs in the body. The treatment for adenocarcinoma may also depend on the stage of the cancer.

Following tests are performed to determine the stage of the cancer include:

  • Imaging tests such as CT scans, x-rays, MRI, PET
  • Bone scans to see if cancer has affected your bones

Biospecimens

biospecimens

Bay Biosciences is a global leader in providing researchers with high quality, clinical grade, fully characterized human tissue samples, bio-specimens, and human bio-fluid collections.

Moreover, human biospecimens are available including tumor tissue, serum, plasma and PBMC samples from most other therapeutic areas.

Furthermore, Bay Biosciences maintains and manages its own biorepository, the human tissue bank (biobank) consisting of thousands of diseased samples (specimens) and likewise normal healthy donors for controls. Additionally, available in all formats and types.

In fact, our biobank procures and stores fully consented, de-identified and institutional review boards (IRB) approved human tissue samples, human biofluids such as serum samples, plasma samples from various diseases and matched controls.

Also, all our human tissue collections, human biospecimens and human biofluids are provided with detailed, samples associated patient’s clinical data.

In fact, this critical patient’s clinical data includes information relating to their past and current disease, treatment history, lifestyle choices, biomarkers, and genetic information.

Additionally, researchers find the patient’s data associated with the human biospecimens extremely valuable and use it to help identify new effective treatments (drug discovery & development) in oncology, as well as in other therapeutic areas and diseases.

Bay Biosciences banks wide variety of human tissue samples and human biological samples, including fresh frozen human biospecimens cryogenically preserved at – 80°C.

For example fresh frozen tissue samples, tumor tissue samples, formalin-fixed paraffin-embedded (FFPE), tissue slides, with matching human bio-fluids, whole blood and blood-derived products such as human serum, human plasma and human PBMCs.

Bay Biosciences is a global leader in collecting and providing human tissue samples according to the specified requirements and customized, tailor-made collection protocols.

Please contact us anytime to discuss your special research projects and customized human tissue sample requirements.

Types of Biospecimens

Bay Biosciences provides human tissue samples (human specimens) and human biofluids from diseased and normal healthy donors which includes:

Moreover, we can also procure most human biospecimens and human biofluids, special collections and requests for human samples that are difficult to find. All our human tissue samples and human biofluids are procured through IRB-approved clinical protocols and procedures.

In addition to the standard processing protocols, Bay Biosciences can also provide human biofluids such as  human plasma, human serum, and human PBMCs bio-fluid samples using custom processing protocols; you buy donor-specific collections in higher volumes and specified sample aliquots from us.

Bay Biosciences also provides human biospecimens from normal healthy donors; volunteers, for controls and clinical research, Contact us Now.