Bay Biosciences provides high quality, clinical grade fresh frozen Biliary Tract Cancer (BTC) Adenocarcinoma tumor tissue specimens, with matched cryogenically preserved sera (serum), plasma and peripheral blood mononuclear cells (PBMC) biofluid samples. The sera and plasma samples are processed from unique patients whole blood following customized protocols, from unique Biliary Tract cancer patients to a valued pharmaceutical customer for research, diagnostics, development and drug discovery.
Biliary Tract Cancer
Biliary tract cancer also known as cholangiocarcinoma is a rare adenocarcinoma that occurs in a bile duct, often causing jaundice, pruritus and weight loss. The lesion may be papillary or flat and ulcerated. Biliary tract cancers (BTCs) are rare with poor prognosis, the tumor is often un-resectable at diagnosis.
The bile ducts are a series of thin tubes that go from the liver to the small intestine. Their major job is to move a fluid called bile from the liver and gallbladder into the small intestine, where it helps digest the fats in food. Most bile duct cancers or cholangiocarcinomas are adenocarcinomas, which are cancers that start in glandular cells. Bile duct adenocarcinomas start in the mucous gland cells that line the inside of the ducts.
Types of Bile Duct Cancers
Cancer can start in any part of the bile duct system, depending on where the cancers are, they are grouped mainly into following three types:
- Intrahepatic bile duct cancers
- Perihilar also knows as hilar bile duct cancers
- Distal bile duct cancers
Intrahepatic Bile Duct Cancers
These cancers start in the smaller bile duct branches inside the liver. Sometimes they’re confused with cancers that start in the liver cells, which are called hepatocellular carcinomas, which are often treated the same way.
Perihilar or Hilar Bile Duct Cancers
Perihilar cancers start at the hilum, where the left and right hepatic ducts have joined and are just leaving the liver, these are also called Klatskin tumors. Perihilar cancers are grouped with distal bile duct cancers as extrahepatic bile duct cancers.
Distal Bile Duct Cancers
These cancers are found further down the bile duct, closer to the small intestine. Like perihilar cancers, these are extrahepatic bile duct cancers because they start outside of the liver.
Detailed clinical data, including genetic test info, KRAS, EGFR, IDH, FGFR and BAP1 and biomarker information including LFT, alkaline phosphatase, AST, ALT, GGT test results are provided. In addition biopsy & pathology annotations, with the patients history associated with the Biliary Tract cancer samples is provided to a valued customer for drug discovery, development and research. The sera (serum) and plasma samples were processed using customized protocols provided by the researcher. Bay Biosciences specializes in providing researchers with customized human samples bio-specimens collections.
Bay Biosciences is a global leader in providing researchers with high quality, clinical grade, fully characterized human tissue samples, bio-specimens and human bio-fluid collections from cancer (tumor) tissue, cancer sera (serum), cancer plasma, cancer PBMC and human tissue samples from most other therapeutic areas and diseases.
Bay Biosciences maintains and manages it’s own bio-repository, human tissue bank (biobank) consisting of thousands of diseased samples (specimens) and from normal healthy donors available in all formats and types. Our biobank procures and stores fully consented, deidentified and institutional review boards (IRB) approved human tissue samples and matched controls.
All our human human tissue collections, human specimens and human bio-fluids are provided with detailed samples associated patient’s clinical data. This critical patient’s clinical data includes information relating to their past and current disease, treatment history, lifestyle choices, biomarkers and genetic information. Patient’s data is extremely valuable for researchers and is used to help identify new effective treatments (drug discovery & development) in oncology, other therapeutic areas and diseases. This clinical information is critical to demonstrate their impact, monitor the safety of medicines, testing & diagnostics, and generate new knowledge about the causes of disease and illness.
Bay Biosciences banks wide variety of human tissue samples and biological samples including cryogenically preserved -80°C, fresh, fresh frozen tissue samples, tumor tissue samples, FFPE’s, tissue slides, with matching human bio-fluids, whole blood and blood derived products such as serum, plasma and PBMC’s.
Bay Biosciences is a global leader in collecting and providing human tissue samples according to the researchers specified requirements and customized, tailor made collection protocols. Please contact us anytime to discuss your special research projects and customized human tissue sample requirements.
Bay Biosciences provides human tissue samples (human specimens) from diseased and normal healthy donors; including peripheral whole-blood, amniotic fluid, bronchoalveolar lavage fluid (BAL), sputum, pleural effusion, cerebrospinal fluid (CSF), serum (sera), plasma, peripheral blood mononuclear cells (PBMC’s), saliva, Buffy coat, urine, stool samples, aqueous humor, vitreous humor, kidney stones, renal calculi, nephrolithiasis, urolithiasis and other bodily fluids from most diseases including cancer. We can also procure most human bio-specimens and can do special collections and requests of human samples that are difficult to find. All our human tissue samples are procured through IRB approved clinical protocols and procedures.
In addition to the standard processing protocols Bay Biosciences can also provide human plasma, serum, PBMC bio-fluid samples using custom processing protocols, you can buy donor specific sample collections in higher volumes and specified sample aliquoting from us. Bay Biosciences also provides human samples from normal healthy donors, volunteers, for controls and clinical research, contact us Now.
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