Bay Biosciences provides high quality, clinical grade, fully characterized, consented human tissue samples from cancer and most other diseases for research. Moreover, Bay Biosciences provide human tissue specimens in all formats including surgically resected fresh frozen tissue samples, tumor tissue samples.

Additional, formalin Fixed Paraffin Embedded (FFPE), OCT, slides, Bio-fluids such as whole-blood and blood derived products such as sera (serum), plasma and peripheral blood mononuclear cells (PBMC) and other body fluids.

What is Cancer?

Cancer is a large group of diseases with one thing in common: they happen when normal cells become cancerous cells that multiply and spread. Specifically, your genes send instructions to your cells — like when to start and stop growing, for example. In contrast, normal cells follow these instructions, but cancer cells ignore them.

Consequently, cancer is the second most common cause of death in the U.S. However, fewer people are dying of cancer now than 20 years ago. This is largely due to early detection and innovative treatments that cure cancer and help people with cancer live longer.

Types of Cancer

Furthermore, there are  over 100 types of cancer. Healthcare providers categorize them according to where they start in your body and the type of tissue they affect. To illustrate, there are three broad cancer classifications:

  • Firstly, solid cancers: this is the most common type of cancer, making up about 80% to 90% of all cases. This includes carcinoma that forms in epithelial tissue (like your skin, breast, colon, and lungs) and sarcoma that forms in bone and connective tissues.
  • Secondly, blood cancers: these are cancers that start in your blood cells or lymphatic system. For example, examples include leukemia, lymphoma, and multiple myeloma.

Prevalence of Cancer

Cancer is, indeed, the second most common cause of death worldwide. Furthermore, researchers estimate that in 2024, over over 2 million people living in the U.S. will receive a cancer diagnosis, and, in addition, over 611,000 people will die from the disease.

Moreover, about 1 in 4 people will develop cancer at some point during their lifetime.

Specifically, the most common cancers in the U.S. are:

Notably, anyone can develop cancer; however, cases vary based on race and sex. According to the 2022 Annual Report on Cancer, the disease:

  • Firstly, affects slightly more men than women.
  • Secondly, affects people over 60 more than any other age group.
  • Moreover, affects more Black men than those in other racial groups.
  • Furthermore, affects more women who are American Indian or Alaska Natives than those in other racial groups.

Symptoms of Cancer

Symptoms of cancer vary from person to person. Specifically, they depend on what type of cancer you have and how advanced it is.

In general, cancer symptoms may include:

Furthermore, in some cases, cancer may cause additional organ-specific symptoms. These may include:

  • First, blood in your pee or in your stool
  • Moreover, changes in the shape, color, or size of a skin mole
  • Likewise, coughing up blood
  • Finally, new lumps or bumps.

However, this isn’t an exhaustive list. Moreover, having these symptoms doesn’t necessarily mean you have cancer.

In fact, cancer is a complicated disease. Different types cause different symptoms. Additionally, it’s also possible to have cancer for years without knowing it. On the other hand, other times, it can cause obvious symptoms that get worse very quickly.

Therefore, a good rule of thumb is to let a healthcare provider know any time there’s a change in your body that lasts for more than two weeks.

Causes of Cancer

Cancer is a genetic disorder. However, that doesn’t necessarily mean it’s inherited. Indeed, genes that manage cell activity mutate (change) when they are affected. As a result, they create abnormal cells that divide and multiply, eventually disrupting how your body works.

In addition, these cells create cancer clusters, or tumors. Furthermore, cancerous cells may break away from tumors and travel to other areas of your body through your lymphatic system or bloodstream. This is known as metastasis.

For example, a tumor in your breast may spread to your lungs, consequently making it hard for you to breathe. Moreover, in some types of blood cancer, your bone marrow makes abnormal blood cells that multiply uncontrollably.

Eventually, the abnormal cells crowd out normal blood cells. According to medical researchers, inherited genetic mutations (changes you can’t control) cause about  5% to 10% of all cancers.

On the other hand, more often, cancer occurs as an acquired genetic mutation (change). This means it happens over the course of your life. Furthermore, medical researchers have identified several risk factors that increase your chance of developing cancer.

Bay Biosciences currently provide services for research programs in the following therapeutic areas:

  • Solid Tumor Oncology
  • Hematologic Malignancies
  • Inflammation
  • Neurological Diseases
  • Infectious Diseases
  • Normal Tissues
  • Other Indications

 

Biospecimens

biospecimens

Bay Biosciences is a global leader in providing researchers with high quality, clinical grade, fully characterized human tissue samples, bio-specimens, and human bio-fluid collections.

Moreover, human biospecimens are available including tumor tissue, serum, plasma and PBMC samples from most other therapeutic areas.

Furthermore, Bay Biosciences maintains and manages its own biorepository, the human tissue bank (biobank) consisting of thousands of diseased samples (specimens) and likewise normal healthy donors for controls. Additionally, available in all formats and types.

In fact, our biobank procures and stores fully consented, de-identified and institutional review boards (IRB) approved human tissue samples, human biofluids such as serum samples, plasma samples from various diseases and matched controls.

Also, all our human tissue collections, human biospecimens and human biofluids are provided with detailed, samples associated patient’s clinical data.

In fact, this critical patient’s clinical data includes information relating to their past and current disease, treatment history, lifestyle choices, biomarkers, and genetic information.

Additionally, researchers find the patient’s data associated with the human biospecimens extremely valuable and use it to help identify new effective treatments (drug discovery & development) in oncology, as well as in other therapeutic areas and diseases.

Bay Biosciences banks wide variety of human tissue samples and human biological samples, including fresh frozen human biospecimens cryogenically preserved at – 80°C.

For example fresh frozen tissue samples, tumor tissue samples, formalin-fixed paraffin-embedded (FFPE), tissue slides, with matching human bio-fluids, whole blood and blood-derived products such as human serum, human plasma and human PBMCs.

Bay Biosciences is a global leader in collecting and providing human tissue samples according to the specified requirements and customized, tailor-made collection protocols.

Please contact us anytime to discuss your special research projects and customized human tissue sample requirements.

Types of Biospecimens

Bay Biosciences provides human tissue samples (human specimens) and human biofluids from diseased and normal healthy donors which includes:

Moreover, we can also procure most human biospecimens and human biofluids, special collections and requests for human samples that are difficult to find. All our human tissue samples and human biofluids are procured through IRB-approved clinical protocols and procedures.

In addition to the standard processing protocols, Bay Biosciences can also provide human biofluids such as  human plasma, human serum, and human PBMCs bio-fluid samples using custom processing protocols; you buy donor-specific collections in higher volumes and specified sample aliquots from us.

Bay Biosciences also provides human biospecimens from normal healthy donors; volunteers, for controls and clinical research, Contact us Now.