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Unexplained Weight Loss Overview

Unexplained weight loss is a significant reduction in body weight that occurs unintentionally, weight loss occurs even if the person is not trying to lose weight. Unexplained weight loss can be a symptom of a serious disease or health conditions, including cancer or diabetes.  It is important to seek medical attention if a person have weight loss that cannot be explained.

Clinical Definition of Unexplained Weight Loss

Unexplained weight loss is a noticeable drop in body weight that occurs even if the person is not intentionally trying to lose weight. The weight loss does not happen because of special diet, exercise or lifestyle changes. Weight loss of 10 pounds or more, or five percent of body weight, over a period of 6 to 12 months is considered unexplained.

Risk Factors of Unexplained Weight Loss

Unexplained weight loss can happen to anyone. It is most common and more serious in older people over the age of 65. Unexplained weight loss of less than fi percent of body weight or 10 pounds may be the sign of a serious health condition or disease in older people.

Causes of Unexplained Weight Loss

Following are some of the health conditions and diseases that can cause unexplained weight loss. These conditions could be caused by diseases that range from mild to very serious conditions. These causes can be physical or psychological:

  • Addison’s disease
  • AIDS
  • Alcohol or drug abuse
  • Anxiety
  • Cancer
  • Celiac Disease (gluten intolerance)
  • Crohn’s disease (an inflammation of the bowels)
  • Dental problems
  • Dementia
  • Depression
  • Diabetes 
  • Drug abuse
  • Dysphagia (swallowing problems)
  • Heart failure
  • Parkinson’s disease 
  • Gastrointestinal problems, such as ulcerative colitis or peptic ulcers
  • Dental problems
  • Swelling of pancreas
  • Side effects of prescription medications
  • An overactive or underactive thyroid gland
  • A parasitic infection
  • Undiagnosed eating disorders

Bay Biosciences is a global leader in providing researchers with high quality, clinical grade, fully characterized human tissue samples, bio-specimens and human bio-fluid collections. 

Samples available are cancer (tumor) tissue, cancer serum, cancer plasma cancer PBMC and human tissue samples from most other therapeutic areas and diseases.

Bay Biosciences maintains and manages its own bio-repository, human tissue bank (biobank) consisting of thousands of diseased samples (specimens) and from normal healthy donors available in all formats and types.

Our biobank procures and stores fully consented, deidentified and institutional review boards (IRB) approved human tissue samples and matched controls.

All our human tissue collections, human specimens and human bio-fluids are provided with detailed samples associated patient’s clinical data.

This critical patient’s clinical data includes information relating to their past and current disease, treatment history, lifestyle choices, biomarkers and genetic information.

Patient’s data is extremely valuable for researchers and is used to help identify new effective treatments (drug discovery & development) in oncology, other therapeutic areas and diseases. 

This clinical information is critical to demonstrate their impact, monitor the safety of medicines, testing & diagnostics, and generate new knowledge about the causes of disease and illness. 

Bay Biosciences banks wide variety of human tissue samples and biological samples including cryogenically preserved at – 80°C.

Including fresh frozen tissue samplestumor tissue samples, FFPE’s, tissue slides, with matching human bio-fluids, whole blood and blood derived products such as serumplasma and PBMC’s.

Bay Biosciences is a global leader in collecting and providing human tissue samples according to the researchers specified requirements and customized, tailor-made collection protocols.

Please contact us anytime to discuss your special research projects and customized human tissue sample requirements.

Bay Biosciences provides human tissue samples (human specimens) from diseased and normal healthy donors which includes:

  • Peripheral whole-blood,
  • Amniotic fluid
  • Bronchoalveolar lavage fluid (BAL)
  • Sputum
  • Pleural effusion
  • Cerebrospinal fluid (CSF)
  • Serum (sera)
  • Plasma
  • Peripheral blood mononuclear cells (PBMC’s)
  • Saliva
  • Buffy coat
  • Urine
  • Stool samples
  • Aqueous humor
  • Vitreous humor
  • Kidney stones (renal calculi)
  • Other bodily fluids from most diseases including cancer.

We can also procure most human bio-specimens and can-do special collections and requests of human samples that are difficult to find. All our human tissue samples are procured through IRB approved clinical protocols and procedures. 

In addition to the standard processing protocols Bay Biosciences can also provide human plasmaserum, PBMC bio-fluid samples using custom processing protocols, you can buy donor specific sample collections in higher volumes and specified sample aliquoting from us.

 Bay Biosciences also provides human samples from normal healthy donors, volunteers, for controls and clinical research, contact us Now.

 

日本のお客様は、ベイバイオサイエンスジャパンBay Biosciences Japanまたはhttp://baybiosciences-jp.com/contact/までご連絡ください。