Sputum Samples from COPD Patients for Research
Bay Biosciences provides sputum samples from moderate to severe chronic obstructive pulmonary disease (COPD) patients with detailed clinical info to a pharmaceutical customer for drug discovery, development and research.
Chronic Obstructive Pulmonary Disease (COPD) Overview
Chronic obstructive pulmonary disease (COPD) describes a chronic inflammatory disease of the lungs that blocks the airways, causing cough with mucus, wheezing, and shortness of breath.
Moreover, COPD primarily serves as an umbrella term for two conditions: emphysema and chronic bronchitis. Specifically, patients with COPD may experience one or both of these issues, and the severity of each varies from person to person.
Emphysema
In particular, emphysema damages the air sacs of the lungs, leading to a loss of elasticity, which ultimately prevents the lungs from efficiently exchanging oxygen and carbon dioxide.
Chronic Bronchitis
Chronic bronchitis causes inflammation of the lining of the airways. Consequently, this leads to increased production and thickening of mucus. When, however, bronchitis persists and resists treatment, it becomes chronic.
Asthma
Moreover, asthma symptoms can contribute to COPD; furthermore, a history of asthma can increase the risk of developing the condition. Specifically, asthma triggers inflammation of the airways, which, in turn, spasm and overreact to inhaled substances.
In addition, COPD presents as a lifelong issue that results in irreversible damage to the lungs, thereby leading to worsening difficulty breathing and airway obstruction. For instance, a person with advanced COPD may struggle to climb the stairs or cook. As a result, they may require medications and supplementary oxygen.
Chronic obstructive pulmonary disease (COPD) debilitate 1 in 8 Americans age 45 and older. Doctors have diagnosed more than 16 million Americans with COPD, and millions more have it but don’t know it.
The condition causes increasing breathlessness, with symptoms developing slowly. Although researchers have not found a cure for COPD yet, they often prevent and treat it. Smoking commonly causes the disease.
More than 65 million people around the world have moderate or severe COPD, and experts predict that this number will continue to rise worldwide over the next 50 years.
With proper management, however, most people with COPD can achieve good symptom control and quality of life, as well as reduce their risk of other associated diseases including heart disease and lung cancer.
More than 65 million people around the world have moderate or severe COPD, and experts predict that the number of people with COPD will continue to rise worldwide over the next 50 years.
With proper management, however, most people with COPD can achieve good symptom control and a good quality of life, as well as reduce their risk of other associated diseases, including heart disease and lung cancer.
Signs and Symptoms of Chronic Obstructive Pulmonary Disease (COPD)
COPD causes some or all of the following signs and symptoms:
- First, a persistent cough
- Additionally, chest tightness
- Furthermore, difficulty breathing that worsens over time
- Moreover, fatigue
- In addition, frequent respiratory infections
- Also, an inability to breath easily or take a deep breath
- Furthermore, excess production of mucus
- Finally, Shortness of breath, especially after exertion
- Lastly, wheezing
A COPD patient with severe symptoms may also have:
- In particular, a rapid heartbeat
- Additionally, bluish tint to the lips or fingernail beds
- Moreover, reduced mental alertness
- Furthermore, shortness of breath while talking
Therefore, anyone with any severe symptoms of COPD should receive immediate medical care.
Consequently, as COPD progresses, there may be swelling in the legs and feet. Low oxygen levels in your bloodstream may result in gray or blue discoloration of your lips and fingernails. Moreover, you may also experience increased weight loss.
In addition, if symptoms are mild, a person may not realize that they have COPD. Therefore, almost 6.4% of the U.S. population have diagnosed COPD, but its actual prevalence may be far more extensive.
Biospecimens
Bay Biosciences is, indeed a global leader in providing researchers with high quality, clinical grade, fully characterized human tissue samples, bio-specimens, and human bio-fluid collections.
Specifically, aamples available include cancer (tumor) tissue, cancer serum, cancer plasma, cancer, peripheral blood mononuclear cells (PBMC). and human tissue samples from most other therapeutic areas and diseases.
Moreover, Bay Biosciences maintains and manages its own biorepository, the human tissue bank (biobank) consisting of thousands of diseased samples (specimens) and from normal healthy donors available in all formats and types.
In fact, our biobank procures and stores fully consented, de-identified and institutional review boards (IRB) approved human tissue samples and matched controls.
Additionally, all our human tissue collections, human specimens and human bio-fluids are provided with detailed, samples associated patient’s clinical data.
In particular, critical patient’s clinical data includes information relating to their past and current disease, treatment history, lifestyle choices, biomarkers, and genetic information.
Moreover, patient’s data is extremely valuable for researchers and is used to help identify new effective treatments (drug discovery & development) in oncology, and other therapeutic areas and diseases.
Specifically, Bay Biosciences banks wide variety of human tissue samples and biological samples, including cryogenically preserved at – 80°C.
For example fresh frozen tissue samples, tumor tissue samples, formalin-fixed paraffin-embedded (FFPE), tissue slides, with matching human bio-fluids, whole blood and blood-derived products such as serum, plasma and PBMC.
Furthermore, Bay Biosciences is a global leader in collecting and providing human tissue samples according to the specified requirements and customized, tailor-made collection protocols.
Therefore, please contact us anytime to discuss your special research projects and customized human tissue sample requirements.
Types of Biospecimens
Bay Biosciences provides human tissue samples (human specimens) from diseased and normal healthy donors which includes:
- Peripheral whole-blood
- Amniotic fluid
- Bronchoalveolar lavage fluid (BAL)
- Sputum
- Pleural effusion
- Cerebrospinal fluid (CSF)
- Serum (sera)
- Plasma
- Peripheral blood mononuclear cells (PBMC)
- Saliva
- Buffy coat
- Urine
- Stool samples
- Aqueous humor
- Vitreous humor
- Kidney stones (renal calculi)
- Other bodily fluids from most diseases including cancer.
Customized Collections
Moreover, we can also procure most human bio-specimens. Furthermore; we offer special collections and requests for human samples that are difficult to find. All our human tissue samples are procured through IRB-approved clinical protocols and procedures.
In addition to the standard processing protocols, Bay Biosciences can also provide human plasma, serum, and PBMC bio-fluid samples using custom processing protocols. Additionally you buy donor-specific collections in higher volumes and specified sample aliquots from us.
Furthermore, Bay Biosciences also provides human samples from normal healthy donors; volunteers, for controls and clinical research, contact us Now.
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