Bay Biosciences provides high quality, clinical grade bio-samples, biopsy tissue samples, FFPE tissue blocks, sera (serum), plasma and peripheral blood mononuclear cells (PBMC) biofluid specimens from patients diagnosed with Coronary Artery Disease. The PBMC, sera (serum) and plasma samples are processed from patient’s peripheral whole-blood using customized processing protocols.

The sera (serum), plasma and PBMC biofluid specimens are processed from coronary artery disease patient’s peripheral whole-blood using customized collection and processing protocols. The coronary artery disease tissue and matched biofluid samples are collected from unique patients diagnosed with coronary artery disease. Samples and are provided to a valued pharmaceutical customer for research, diagnostics, discovery and drug development.

Detailed clinical data, coronary artery disease  patient’s history, symptoms, complete blood count (CBC), serology, MRI, biopsy tissue, histopathology information, elevated biomarker levels, genetic and metabolic information. The coronary artery disease specimens are provided to a valued customer for research, development and drug discovery.

The coronary artery disease sera (serum), plasma and peripheral blood mononuclear cells (PBMC) biofluids are processed from patients peripheral whole-blood using customized collection and processing. protocols.

Coronary Artery Disease (CAD) Overview

Coronary artery disease is a narrowing or blockage of the coronary arteries caused by the buildup of plaque in the arteries that supply oxygen-rich blood to the heart. Plaque is a fatty material which causes a narrowing or blockage caused by the plaque could result in a heart attack. Coronary artery disease is also called coronary heart disease, ischemic heart disease and heart disease.

What is Coronary Artery Disease (CAD)?

Coronary artery disease (CAD) develops when, as a result of plaque building up in the coronary arteries, they become narrow or blocked. Consequently, it can lead to a heart attack. However, statins and other treatment options can help.

Furthermore, CAD, or coronary heart disease, tends to develop when cholesterol builds up on the artery walls, thereby creating plaques. These plaques can, in turn, narrow the arteries, reducing blood flow to the heart, or cause inflammation in and hardening of the blood vessel walls. Additionally, a clot can sometimes obstruct blood flow, causing serious health problems.

Moreover, coronary arteries form the network of blood vessels on the surface of the heart that provides oxygen to it. If these arteries narrow, then the heart may not receive enough oxygen-rich blood, especially during physical activity.

In addition, high cholesterol, smoking, and other factors increase the risk of developing the condition.

Ultimately, CAD can sometimes lead to a heart attack. According to the Centers for Disease Control and Prevention (CDC), CAD is, in fact, the most common type of heart disease in the U.S. and accounted for 382,820 deaths.

Causes of CAD

CAD occurs when fatty plaque deposits build up in the arteries that supply blood to the heart.

Furthermore, underlying health conditions, such as high cholesterol and diabetes, as well as physical damage to arteries, can cause plaque buildup and lead to CAD. In addition, the condition has many other risk factors as well.

Moreover, the plaque deposits consist of cholesterol and other inflammatory products from cells. Consequently, the buildup of plaque is called atherosclerosis. Over time, plaque deposits can narrow the arteries, thereby restricting or stopping blood flow.

If, for example, pieces of plaque break off or rupture, platelets cluster in the area, forming a blood clot. As a result, blood clots can block the artery and reduce or block blood flow. This, in turn, may lead to a heart attack.

Symptoms of CAD

Specifically, CAD can lead to angina, a type of chest pain that has a link to heart disease.

Angina may cause shortness of breath and the following sensations across the chest:

  • Aching
  • Burning
  • Heaviness
  • Pressure
  • Squeezing
  • Tightening

In addition, angina might also cause the following symptoms:

Biospecimens

biospecimens

Bay Biosciences is a global leader in providing researchers with high quality, clinical grade, fully characterized human tissue samples, bio-specimens, and human bio-fluid collections.

Moreover, human biospecimens are available including tumor tissue, serum, plasma and PBMC Samples from most other therapeutic areas.

Furthermore, Bay Biosciences maintains and manages its own biorepository, the human tissue bank (biobank) consisting of thousands of diseased samples (specimens) and likewise normal healthy donors for controls. Additionally, available in all formats and types.

In fact, our biobank procures and stores fully consented, de-identified and institutional review boards (IRB) approved human tissue samples, human biofluids such as serum samples, plasma samples from various diseases and matched controls.

Also, all our human tissue collections, human biospecimens and human biofluids are provided with detailed, samples associated patient’s clinical data.

In fact, this critical patient’s clinical data includes information relating to their past and current disease, treatment history, lifestyle choices, biomarkers, and genetic information.

Additionally, researchers find the patient’s data associated with the human biospecimens extremely valuable and use it to help identify new effective treatments (drug discovery & development) in oncology, as well as in other therapeutic areas and diseases.

Bay Biosciences banks wide variety of human tissue samples and human biological samples, including fresh frozen human biospecimens cryogenically preserved at – 80°C.

For example fresh frozen tissue samples, tumor tissue samples, formalin-fixed paraffin-embedded (FFPE), tissue slides, with matching human bio-fluids, whole blood and blood-derived products such as human serum, human plasma and human PBMCs.

Bay Biosciences is a global leader in collecting and providing human tissue samples according to the specified requirements and customized, tailor-made collection protocols.

Please contact us anytime to discuss your special research projects and customized human tissue sample requirements.

Types of Biospecimens

Bay Biosciences provides human tissue samples (human specimens) and human biofluids from diseased and normal healthy donors which includes:

Moreover, we can also procure most human biospecimens and human biofluids, special collections and requests for human samples that are difficult to find. All our human tissue samples and human biofluids are procured through IRB-approved clinical protocols and procedures.

In addition to the standard processing protocols, Bay Biosciences can also provide human biofluids such as  human plasma, human serum, and human PBMCs bio-fluid samples using custom processing protocols. you buy donor-specific collections in higher volumes and specified sample aliquots from us in multiple format and sets.

Bay Biosciences also provides human biospecimens from normal healthy donors; volunteers, for controls and clinical research, Contact us Now.