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Stress is a normal reaction the body has when negative changes occur, resulting in physical, emotional and intellectual responses. Stress is a natural feeling of not being able to cope with specific demands and events. Stress is the feeling of being overwhelmed or unable to cope with mental or emotional pressure.

These demands can come from work, relationships, financial pressures, and other situations, but anything that poses a real or perceived challenge or threat to a person’s well-being can cause stress.

Stress can be a motivator, and it can even be essential to survival. The body’s fight-or-flight mechanism tells a person when and how to respond to danger. However, when the body becomes triggered too easily, or there are too many stressors at one time, it can undermine a person’s mental and physical health and become harmful.

The human body is designed to experience stress and react to it. When you experience changes or challenges (stressors), your body produces physical and mental responses, that is stress.

Stress responses help your body adjust to new situations. Stress can be positive, keeping us alert, motivated and ready to avoid danger. For example, if you have an important test coming up, a stress response might help your body work harder and stay awake longer. But stress becomes a problem when stressors continue without relief or periods of relaxation.

Stress can be a short-term issue or a long-term problem, depending on what changes in your life. Regularly using stress management techniques can help you avoid most physical, emotional and behavioral symptoms of stress.

Signs and Symptoms of Stress

Following are the common signs and symptoms of stress these feelings can sometimes produce physical symptoms, making you feel even worse.

  • Headaches: Stress can trigger and intensify tension headaches
  • Increased Depression: Chronic stress can wear you down emotionally and lead to depression
  • Heartburn: Stress increases the production of stomach acid which can lead to heartburn or make it worse
  • High Blood Pressure: Stress hormones tightens blood vessels which results in raise in blood pressure.
  • Rapid Breathing: When a person is stressed, the muscles that help you breath tense up, which can lead to shortness of breath
  • Risk of Heart Attack: Increased heart rate and high blood pressure damage the arteries over time, which can lead to a heart attack.
  • Stomachache: Stress affects the body’s digestive system, which can lead to stomachache (abdominal pain), nausea and other stomach problems
  • Insomnia: Stress makes it harder to fall asleep and stay asleep, which can lead to insomnia
  • Low Sex Drive: Stress and fatigue that often comes with it, can take a toll on your libido
  • Erectile Dysfunction: The brain plays and important part in the process of getting an erection. Stress can interfere with this process
  • Missed Periods: Fluctuating hormones can throw your normal menstrual cycle off, or in severe cases stop it altogether
  • Fertility Problems: Stress interferes with the reproductive system in both men and women, and may make it harder to conceive.
  • Anger or aggressive behavior
  • Weakened Immune system: Long-term stress weakens your immune system’s defenses, leaving the person more vulnerable to infections  
  • Tense Muscles: Stress makes muscles tense up, and chronic stress can lead to tension related headaches and backaches

 If the stress response doesn’t stop firing, and these stress levels stay elevated far longer than is necessary for survival, it can take a toll on your health. Chronic stress can cause a variety of symptoms and affect persons overall well-being. Following are some of the common symptoms of chronic stress:

Often, patients with chronic stress try to manage it with unhealthy behaviors, including:
  • Drinking too much or too often
  • Gambling
  • Overeating or developing an eating disorder
  • Participating compulsively in sex, shopping or internet browsing
  • Smoking
  • Using drugs

Diagnosis of Stress

Stress is subjective and cannot be measured by tests. Only the person experiencing it can determine whether is it present and how severe it feels. A doctor may use questionnaires to understand your stress and how it affects your life. If you have chronic stress, your healthcare provider can evaluate symptoms that result from stress. For example, high blood pressure can be diagnosed and treated.

 

Bay Biosciences is a global leader in providing researchers with high quality, clinical grade, fully characterized human tissue samples, bio-specimens and human bio-fluid collections from cancer (tumor) tissue, cancer serum, cancer plasma cancer PBMC and human tissue samples from most other therapeutic areas and diseases.

Bay Biosciences maintains and manages it’s own bio-repository, human tissue bank (biobank) consisting of thousands of diseased samples (specimens) and from normal healthy donors available in all formats and types. Our biobank procures and stores fully consented, deidentified and institutional review boards (IRB) approved human tissue samples and matched controls.

All our human human tissue collections, human specimens and human bio-fluids are provided with detailed samples associated patient’s clinical data. This critical patient’s clinical data includes information relating to their past and current disease, treatment history, lifestyle choices, biomarkers and genetic information. Patient’s data is extremely valuable for researchers and is used to help identify new effective treatments (drug discovery & development) in oncology, other therapeutic areas and diseases. This clinical information is critical to demonstrate their impact, monitor the safety of medicines, testing & diagnostics, and generate new knowledge about the causes of disease and illness. 

Bay Biosciences banks wide variety of human tissue samples and biological samples including cryogenically preserved -80°C, fresh, fresh frozen tissue samplestumor tissue samples, FFPE’s, tissue slides, with matching human bio-fluids, whole blood and blood derived products such as serumplasma and PBMC’s.

Bay Biosciences is a global leader in collecting and providing human tissue samples according to the researchers specified requirements and customized, tailor made collection protocols. Please contact us anytime to discuss your special research projects and customized human tissue sample requirements.

Bay Biosciences provides human tissue samples (human specimens) from diseased and normal healthy donors; including peripheral whole-blood, amniotic fluid, bronchoalveolar lavage fluid (BAL), sputum, pleural effusion, cerebrospinal fluid (CSF), serum (sera), plasma, peripheral blood mononuclear cells (PBMC’s), saliva, Buffy coat, urine, stool samples, aqueous humor, vitreous humor, kidney stones, renal calculi, nephrolithiasis, urolithiasis and other bodily fluids from most diseases including cancer. We can also procure most human bio-specimens and can do special collections and requests of human samples that are difficult to find. All our human tissue samples are procured through IRB approved clinical protocols and procedures. 

In addition to the standard processing protocols Bay Biosciences can also provide human plasmaserum, PBMC bio-fluid samples using custom processing protocols, you can buy donor specific sample collections in higher volumes and specified sample aliquoting from us. Bay Biosciences also provides human samples from normal healthy donors, volunteers, for controls and clinical research, contact us Now.

 

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