+1-617-394-8820 contact@baybiosciences.com

Constipation Overview

Constipation is when a person has difficulty passing stool. It can also cause pain, bloating, nausea, and other symptoms. Depending on the cause, medical treatments and home remedies may help.

Although, constipation can happen for many reasons, such as when stool passes through the colon too slowly. However, the slower the food moves through the digestive tract, the more water the colon absorbs, and the harder feces becomes.

Moreover, constipation results from a blockage in the large or small intestine. In this case, a person needs urgent medical attention. At other times, it may be due to a lack of fiber or water.


Symptoms of Constipation

The main symptoms of constipation are:

  • Difficulty passing stool
  • Having fewer than three bowel movements per week
  • Lumpy, dry, or hard stool
  • Passing less stool than usual
  • Straining when passing stool

In addition, other symptoms include:


Causes of Constipation

There are numerous possible causes of constipation.

Lack of Fiber in the Diet

Not getting enough dietary fiber may lead to constipation. Hence, this is because fiber promotes regular bowel movements, especially when a person combines it with proper hydration.

Examples of high fiber foods include:

  • Fruits
  • Lentils, chickpeas, and other legumes
  • Nuts
  • Vegetables
  • Whole grains

Physical Inactivity

Low levels of physical activity or not getting enough exercise may also lead to constipation.

However, researchers do not know exactly why not getting enough physical activity can cause constipation. However, they believe it may be because physical activity helps stool pass through the colon.

Certain Medications

Moreover, some medications can increase the risk of constipation. These include the following:

  • Anticonvulsants
  • Calcium channel blockers
  • Antacids containing calcium and aluminum
  • Diuretics
  • Anticholinergics
  • Narcotic pain medications
  • Antispasmodic

However, it is best for a person to contact a doctor if they believe medication they are taking may be causing constipation.


Medical Conditions

Some medical conditions can cause or increase a person’s risk of constipation. These include:

Treating the underlying medical condition may help alleviate symptoms of constipation.

Other causes

Other possible causes of constipation include:

Constipation in Babies and Infants

In fact, constipation can sometimes affect babies and infants.

Furthermore, if a newborn does not pass meconium, their first solid stool, within 48 hours of birth, they may have Hirschsprung’s disease. Hence, this is a condition where certain nerve cells are missing from part of the large intestine. Likewise, stool is unable to move forward in the affected area of the colon, which causes a backup.

Therefore, a healthcare professional will usually be able to spot these symptoms and recommend surgery as treatment. However, in most cases, the outlook is good for babies born with this condition.

Constipation can occur in young infants:

  • During weaning
  • At times of stress, such as when starting school
  • During potty training


Constipation in Pregnancy

According to the U.K.’s National Childbirth Trust, around 40% of people experience constipation during pregnancy. It may be particularly common toward the end of pregnancy.

Moreover, this can result from the following:

  • Dietary changes
  • Hormonal changes
  • Physical changes, such as when the uterus presses on the intestines
  • Reduced physical activity


Home Remedies for Constipation

Although, various home treatments can help manage constipation, such as drinking more water and eating fiber. However, if home remedies do not help, over-the-counter and prescription medications are available.

In fact, constipation affects around 20% of people in the United States, resulting in 8 million doctor visits per year.

Accordingly, people may experience constipation due to the foods they eat or avoid, their lifestyle choices, the medications they take, or the medical conditions they have. However, for many, the cause of their chronic constipation is unknown. Moreover, this is known as chronic idiopathic constipation.

Constipation is characterized by the following symptoms:

  • A feeling that not all stool has passed
  • Difficulty or pain when passing stools
  • Fewer than three bowel movements per week
  • Hard, dry, or lumpy stools

Consequently, constipation can have a serious negative effect on quality of life, as well as on physical and mental health.

Although there are many natural ways to help relieve constipation. Furthermore, people can do these in the comfort of their own homes, and most of them are supported by science.

Following are 13 natural home remedies to relieve constipation:

1. Drink More Water

Being dehydrated regularly can make a person constipated. To prevent this, it is important to drink enough water and stay hydrated.

When a person is constipated, they might find relief from drinking some carbonated (sparkling) water. This can help them rehydrate and get things moving again.

Some studies have found sparkling water to be more effective than tap water at relieving constipation. This includes in people with indigestion, or dyspepsia, and people with chronic idiopathic constipation.

However, drinking carbonated drinks such as sugary soda is not a good idea, as these beverages can have harmful health effects and may make constipation worse.

Some people with irritable bowel syndrome (IBS) find that carbonated drinks worsen their symptoms, so these individuals may wish to avoid sparkling water and other carbonated drinks.

Bottom line: Dehydration can cause constipation, so be sure to drink enough water. Sparkling water may be even more effective at relieving constipation.


2. Eat more Fiber, especially Soluble, Non-fermentable fiber

To treat constipation, doctors often tell people to increase their dietary fiber intake.

This is because increasing fiber intake increases the bulk and consistency of bowel movements, making them easier to pass. It also helps them pass through the digestive system more quickly.

In fact, one 2016 review found that 77% of people with chronic constipation benefited from supplementing with fiber.

However, some studies have found that increasing fiber intake can actually make the problem worse. Others report that dietary fiber improves stool frequency but may not help with other symptoms of constipation, such as stool consistency, pain, bloating, and gas.

This is because different types of dietary fiber have different effects on digestion.

There are many different dietary fibers, but in general, they fall into two categories: insoluble fibers and soluble fibers.

Insoluble Fibers

Insoluble fibers — present in wheat bran, vegetables, and whole grains — add bulk to stools and may help them pass more quickly and easily through the digestive system.

Soluble Fibers

Soluble fibers — present in oat bran, barley, nuts, seeds, beans, lentils, and peas, as well as some fruits and vegetables — absorb water and form a gel-like paste, which softens the stools and improves its consistency.

Non-fermentable soluble fibers, such as psyllium, are the best choice for treating constipation.

Psyllium

One 2020 review found psyllium to be 3.4 times more effective than insoluble wheat bran for constipation.

Studies examining the effects of insoluble fiber as a treatment for constipation have yielded mixed results.

This is partly because insoluble fiber can make the problem worse in some people with a functional bowel problem, such as IBS or chronic idiopathic constipation.

Some fermentable soluble fibers may also be ineffective at treating constipation, as they are fermented by bacteria in the gut and lose their water-holding capacity.

To prevent constipation, people should aim to consume a mix of soluble and insoluble fibers. The total recommended fiber intake per day is 25 grams (g) for females and 38 g for males.

Bottom line: Try eating more high fiber foods. Supplementing the diet with soluble non-fermentable fiber, such as psyllium, can also help.


3. Exercise more

Various research studies have reported that exercise could help improve the symptoms of constipation.

Studies have linked sedentary lifestyles with an increased risk of constipation. Because of this, some healthcare experts recommend increasing exercise to get the stool moving.

That said, not all studies agree that exercise treats constipation. Therefore, more research is needed.

Other studies have reported that although exercise did not always improve the number of times people went to the bathroom, it did reduce some symptoms and improved people’s quality of life scores.

In people with IBS, moderate exercise (brisk walking) can improve digestive symptoms and quality of life scores. However, vigorous exercise (jogging) could make symptoms worse for some.

Try doing some gentle exercise — such as going for regular walks, swimming, cycling, or jogging — to see if it helps.

Bottom line: Exercise may reduce the symptoms of constipation in some people.


4. Drink coffee, especially caffeinated coffee

For some people, consuming coffee can increase the urge to go to the bathroom. This is because coffee stimulates the muscles in the digestive system.

In fact, one 1998 study found that caffeinated coffee can stimulate the gut in the same way that a meal can. This effect was 60% stronger than drinking water and 23% stronger than drinking decaffeinated coffee.

Coffee may also contain small amounts of soluble fibers that help prevent constipation by improving the balance of gut bacteria.

That said, the bowel-stimulating qualities of caffeine may be stronger in people with IBS. It could also make digestive symptoms worse..

People with IBS can try removing caffeine from their diet to see if it helps.

Bottom line: Coffee can help relieve constipation by stimulating the muscles in the gut. It may also contain small amounts of soluble fiber.


5. Take Senna, an herbal laxative

Senna is a popular safe and effective herbal laxative that helps treat constipation. It is available over the counter and online, in both oral and rectal forms.

Senna contains plant compounds called glycosides, which stimulate the nerves in the gut and help speed up bowel movements..

Doctors consider Senna safe for adults for short periods of time, but people should consult a doctor if their symptoms do not go away after a few days.

Doctors usually do not recommend Senna for pregnant women, those who are breastfeeding, or people with certain health conditions, such as inflammatory bowel disease.

Bottom line: The herbal laxative Senna is a popular remedy for constipation. It stimulates the nerves in the gut to speed up bowel movements.


6. Eat probiotic foods or take probiotic supplements

Probiotics may help prevent chronic constipation. Probiotics are live, beneficial bacteria that naturally occur in the gut. They include Bifidobacteria and Lactobacillus.

People can increase their levels by eating probiotic foods.

Some people who have chronic constipation have an imbalance of bacteria in their gut. Consuming more probiotic foods could help improve this balance and prevent constipation.

One study mentioned in a 2019 review found that taking probiotics for 2 weeks can help treat constipation, increasing stool frequency and stool consistency.

They could also help treat constipation by producing short-chain fatty acids. These may improve gut movements, making it easier to pass stools.

Alternatively, try a probiotic supplement. Some studies have found that people started to feel the benefits of these supplements after 4 weeks.

Try taking probiotic supplements, which are available online, or eating more probiotic-rich foods to see if this helps with constipation. Probiotic foods include:

  • Kimchi
  • Sauerkraut
  • Yogurt

Bottom line: Probiotics may help treat chronic constipation. Try eating probiotic foods or taking a supplement.

 

7. Over-the-counter or prescription laxatives

A person can speak to a doctor or pharmacist about choosing an appropriate laxative. Different types have varying methods of action, but all are effective for constipation.

A doctor may recommend one of the following types:

  • Bulking agents: These are fiber-based laxatives that increase the water content of stool.
  • Stool softeners: These contain oils to soften stools and ease their passage through the gut.
  • Stimulant laxatives: These stimulate the nerves in the gut to increase bowel movements.
  • Osmotic laxatives: These soften stool by pulling water from the surrounding tissues into the digestive system.

However, people should not take most of these laxatives on a regular basis without speaking to a doctor.

Bottom line: Laxatives are effective for relieving constipation. Speak to a doctor or pharmacist about the best ones to use.

 

8. Try a low FODMAP diet

Constipation can be a symptom of IBS. The low FOODMAP diet is an elimination diet that helps treat IBS and may relieve IBS-related constipation.

FODMAP stands for fermentable oligosaccharides, disaccharides, monosaccharides, and polyols.

The diet involves limiting high FODMAP foods for a period of time before reintroducing them to determine which ones the body can tolerate.

In people with constipation-predominant IBS, the low FODMAP diet alone is often not enough.

Such people will probably need to pay attention to other aspects of their diet, such as getting enough water and fiber, to experience relief from their symptoms.

Bottom line: A low FODMAP diet may help relieve IBS-related constipation. However, that alone may not provide sufficient relief.

 

9. Eat Shirataki Noodles or take a Glucomannan Supplement

Glucomannan is a type of soluble fiber from the roots of the konjac plant. Some research suggests that it is effective against constipation.

As well as improving bowel movements, glucomannan may act as a prebiotic to improve the balance of good bacteria in the gut.

One review on the effect of glucomannan in children concluded that glucomannan moderately increases defecation but does not increase stool consistency or benefit treatment overall.

However, another controlled study found no significant effects.

People can get glucomannan from supplements or by eating shirataki, or konjac, noodles.

Glucomannan supplements are also available. They vary in their benefits by brand, so it is best to compare brands before making a purchase.

Bottom line: Glucomannan may help treat constipation in some people. Sources include supplements and shirataki noodles.

10. Eat Prebiotic Foods

Probiotics are an indigestible carbohydrate fiber. Prebiotics include oligosaccharide and inulin.

Although dietary fibers reduce constipation by improving the consistency and bulk of stool, prebiotics have their effects by improving digestive health.

Prebiotic fibers improve digestive health by feeding the beneficial bacteria in the gut, which boosts probiotics and improves the balance of the gut bacteria.

In fact, some prebiotics may help increase the frequency of bowel movements, as well as make stools softer.

Probiotic foods include:

  • Bananas
  • Chickpeas
  • Chicory
  • Garlic
  • Jerusalem artichokes
  • Onions
  • Leeks

However, garlic and onions are not included in a low FODMAP diet as these foods can trigger symptoms in people with IBS.

Bottom line: Foods that contain prebiotic fibers can improve digestive health and the balance of beneficial gut bacteria. Prebiotics may help relieve constipation.


11. Try Magnesium Citrate

Magnesium citrate is a popular home remedy against constipation. It is a type of osmotic laxative that people can buy over the counter or online.

Taking moderate amounts of magnesium supplements can help relieve constipation. Doctors use higher dosages to prepare and clean out the bowel before surgery or other medical procedures.

Bottom line: Taking magnesium citrate, an over-the-counter supplement, can help relieve constipation.


12. Eat Prunes

People often tout prunes and prune juice as nature’s remedy for constipation — and for good reason. Prunes may be the most accessible natural solution available.

In addition to fiber, prunes contain sorbitol. This is a sugar alcohol that has a laxative effect.

Some studies have shown that prunes may be more effective than fibers such as psyllium.

The effective dosage may be around 50 g, or seven medium prunes, twice per day.

However, people with IBS may want to avoid prunes, because sugar alcohols are high FODMAP foods.

Bottom line: Prunes contain the sugar alcohol sorbitol, which has a laxative effect. Prunes can be a very effective remedy for constipation.

 

13. Try Avoiding Dairy

In people with an intolerance to it, eating dairy can cause constipation due to its effect on the gut’s movements.

This includes children who are intolerant to cow’s milk protein and adults with lactose intolerence.

If someone suspects a dairy intolerance, they can see their doctor for diagnosis. The doctor may recommend temporarily removing dairy from the diet, while increasing other calcium-rich foods, to see if it improves the symptoms.

Bottom line: Dairy or lactose intolerance may cause constipation in some people. In these people, removing dairy from the diet can help relieve symptoms.

 

Biospecimens

Bay Biosciences is a global leader in providing researchers with high quality, clinical grade, fully characterized human tissue samples, bio-specimens, and human bio-fluid collections.

Samples available include cancer (tumor) tissue, cancer serum, cancer plasma, cancer, peripheral blood mononuclear cells (PBMC). and human tissue samples from most other therapeutic areas and diseases.

Bay Biosciences maintains and manages its own bio-repository, the human tissue bank (biobank) consisting of thousands of diseased samples (specimens) and from normal healthy donors available in all formats and types.

In fact, our biobank procures and stores fully consented, de-identified and institutional review boards (IRB) approved human tissue samples and matched controls.

Our human tissue collections, specimens, and bio-fluids come with detailed patient clinical data associated with them.

So this critical patient’s clinical data includes information relating to their past and current disease, treatment history, lifestyle choices, biomarkers, and genetic information.

Additionally, new effective treatments (drug discovery & development) in oncology, and other therapeutic areas and diseases are identified by researchers using patient’s data which is extremely valuable.

Bay Biosciences banks wide variety of human tissue samples and biological samples, including cryogenically preserved at – 80°C.

For example fresh frozen tissue samplestumor tissue samples, formalin-fixed paraffin-embedded (FFPE), tissue slides, with matching human bio-fluids, whole blood and blood-derived products such as serumplasma and PBMC.

Bay Biosciences is a global leader in collecting and providing human tissue samples according to the specified requirements and customized, tailor-made collection protocols.

Please contact us anytime to discuss your special research projects and customized human tissue sample requirements.

Types of Biospecimens

Bay Biosciences provides human tissue samples (human specimens) from diseased and normal healthy donors which includes:

Moreover, we can also procure most human bio-specimens, special collections and requests for human samples that are difficult to find. All our human tissue samples are procured through IRB-approved clinical protocols and procedures.

In addition to the standard processing protocols, Bay Biosciences can also provide human plasmaserum, and PBMC bio-fluid samples using custom processing protocols; you buy donor-specific collections in higher volumes and specified sample aliquots from us.

Bay Biosciences also provides human samples from normal healthy donors; volunteers, for controls and clinical research, contact us Now.

  • 日本のお客様は、ベイバイオサイエンスジャパンBay Biosciences Japanまたはhttp://baybiosciences-jp.com/contact/までご連絡ください。