Bay Biosciences provides high quality, clinical grade bio-samples, muscle biopsy tissue, sera (serum), plasma and peripheral blood mononuclear cells (PBMC) from patients diagnosed with Polymyositis disease. The PBMC, sera (serum) and plasma samples are processed from patient’s peripheral whole-blood using customized processing protocols.
The human Polymyositis bio-specimens are collected from unique patients diagnosed with Polymyositis disease and provided to a valued pharmaceutical customer for research, development and drug discovery.
Polymyositis is a rare inflammatory disease (Inflammatory myopathy) that causes muscle weakness and pain affecting both sides of the body. It inflames the muscles and their related tissues, like the blood vessels that supply them. The inflammation of polymyositis is mainly found in the endomysial layer (within the muscle) of the skeletal muscle, where as dermatomyositis is characterized primarily by inflammation of the perimysial layer of skeletal muscle.
Polymyositis is an autoimmune disease, which means that the body’s immune system attacks it’s own tissue, which causes the related problems. Polymyositis is more common in patients with other autoimmune conditions like lupus and rheumatoid arthritis, it is also more common with HIV patients. Polymyositis and the associated inflammatory myopathies have an associated increased risk of developing tumors and cancer.
Risk factors for polymyositis include:
- Lupus
- Rheumatoid Arthritis
- Scleroderma
- Sjogren’s Syndrome
- Viral infections like HIV and AIDS
- Pulmonary Diseases that affect patient’s ability to breathe
Symptoms of Polymyositis
The symptoms of polymyositis are caused by inflammation in the muscles. The muscle weakness affects both sides of the body equally. The condition tends to target the muscle groups that are closest to the trunk of the body, the hips, shoulders, thighs, upper arms, upper back, and neck.
Detailed clinical data, elevated biomarker levels, serology, biomarkers, Jo-1, MDA5, TIF1γ, Mi2, PL-7, PL-12, KS, EJ, genetic information, muscle biopsy tissue, pathology annotations, associated with the Polymyositis patient’s specimens is provided to a valued customer for drug discovery, development and research. The Polymyositis disease PBMC, sera (serum) and plasma samples were processed from patients peripheral whole blood using customized processing protocols provided by the researcher. Bay Biosciences specializes in providing researchers with high quality, clinical grade customized human samples, bio-specimens and human bio-fluid collections worldwide.
Bay Biosciences is a global leader in providing researchers with high quality, clinical grade, fully characterized human tissue samples, bio-specimens and human bio-fluid collections from cancer (tumor) tissue, cancer sera (serum), cancer plasma, cancer PBMC and human tissue samples from most other therapeutic areas and diseases.
Bay Biosciences maintains and manages it’s own bio-repository, human tissue bank (biobank) consisting of thousands of diseased samples (specimens) and from normal healthy donors available in all formats and types. Our biobank procures and stores fully consented, deidentified and institutional review boards (IRB) approved human tissue samples and matched controls.
All our human human tissue collections, human specimens and human bio-fluids are provided with detailed samples associated patient’s clinical data. This critical patient’s clinical data includes information relating to their past and current disease, treatment history, lifestyle choices, biomarkers and genetic information. Patient’s data is extremely valuable for researchers and is used to help identify new effective treatments (drug discovery & development) in oncology, other therapeutic areas and diseases. This clinical information is critical to demonstrate their impact, monitor the safety of medicines, testing & diagnostics, and generate new knowledge about the causes of disease and illness.
Bay Biosciences banks wide variety of human tissue samples and biological samples including cryogenically preserved -80°C, fresh, fresh frozen tissue samples, tumor tissue samples, FFPE’s, tissue slides, with matching human bio-fluids, whole blood and blood derived products such as serum, plasma and PBMC’s.
Bay Biosciences is a global leader in collecting and providing human tissue samples according to the researchers specified requirements and customized, tailor made collection protocols. Please contact us anytime to discuss your special research projects and customized human tissue sample requirements.
Bay Biosciences provides human tissue samples (human specimens) from diseased and normal healthy donors; including peripheral whole-blood, amniotic fluid, bronchoalveolar lavage fluid (BAL), sputum, pleural effusion, cerebrospinal fluid (CSF), serum (sera), plasma, peripheral blood mononuclear cells (PBMC’s), saliva, Buffy coat, urine, stool samples, aqueous humor, vitreous humor, kidney stones, renal calculi, nephrolithiasis, urolithiasis and other bodily fluids from most diseases including cancer. We can also procure most human bio-specimens and can do special collections and requests of human samples that are difficult to find. All our human tissue samples are procured through IRB approved clinical protocols and procedures.
In addition to the standard processing protocols Bay Biosciences can also provide human plasma, serum, PBMC bio-fluid samples using custom processing protocols, you can buy donor specific sample collections in higher volumes and specified sample aliquoting from us. Bay Biosciences also provides human samples from normal healthy donors, volunteers, for controls and clinical research, contact us Now.
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