+1-617-394-8820 contact@baybiosciences.com

Blood Pressure Meds Side Effects

by | Jun 27, 2024 | Info | 0 comments

Medications for high blood pressure can help prevent a range of complications, including heart disease and stroke. Lotensin, Inderal, and Teveten are just some of the names your doctor may recommend

According to the American Heart Association, the types of medications a doctor may prescribe are:

  • ACE inhibitors
  • Beta blockers
  • Central agonists
  • Alpha-blockers
  • Diuretics
  • Angiotensin II receptor blockers
  • Calcium channel blockers
  • Alpha-2 receptor agonists
  • Combined alpha- and beta-blockers
  • Peripheral adrenergic inhibitors
  • Vasodilators

This article outlines the various blood pressure medications and their associated side effects and risks.

Diuretics

Excess salt can cause a buildup of fluid within the blood vessels, which raises blood pressure. Diuretics help the body eliminate excess salt and water by increasing urine output.

There are different types of diuretics. Here are some examples:

  • Amiloride hydrochloride (Midamar)
  • Chlorthalidone (Hygroton)
  • Furosemide (Lasix)

Possible side effects of diuretics include:

 

 Drugs that may interact with diuretics include the following:

Diuretics may not be suitable for patients who tend to become dehydrated quickly. They can also make the following conditions worse:


Beta-Blockers

Beta blockers reduce blood pressure by blocking the action of hormones in the nervous system, such as epinephrine, also known as adrenaline.

Here are some examples of beta-blockers:

  • Acebutolol (Sectral)
  • Atenolol (Tenormin) 
  • Propranolol hydrochloride (Inderal)

Some side effects of beta-blockers may include:

  • Fatigue or tiredness
  • weakness or dizziness
  • Cold hands and cold feet
  • Dry mouth, eyes, and skin

Less common side effects include:

  • Depresssion
  • Slow heart rate
  • Insomnia
  • Swelling of the hands or feet
  • Rash or itchy skin
  • low blood pressure
  • Wheezing or difficulty breathing

Some drugs and medications can change the effectiveness of beta-blockers. These include:

  • Alcohol
  • Caffeine
  • Other blood pressure medications
  • Cough and cold medications, including antihistamines and decongestants
  • Insulin and some oral medications for diabetes
  • Allergy shots
  • Medicines to treat asthma, chronic bronchitis, emphysema, or chronic obstructive pulmonary disease (COPD)
  • Some antidepressants

Beta-blockers may not be suitable for patients with the following diseases:


ACE Inhibitors

Angiotensin-converting enzyme (ACE) is an enzyme that causes the body’s blood vessels to narrow, which leads to an increase in a person’s blood pressure.

ACE inhibitors lower blood pressure by blocking ACE, relaxing the blood vessels, and allowing blood to flow more freely.

Examples of ACE inhibitors include:

  • Benazepril hydrochloride (Lotensin)
  • Fosinopril sodium (Monopril)
  • quinapril hydrochloride (Accupril).

This recall is specific only to a handful of lot numbers and does not affect all Accupril tablets made by Pfizer.

A dry cough is the most common side effect of ACE inhibitors.

Less common side effects include:

  • A metallic taste in the mouth
  • Constipation
  • Headaches
  • An upset stomach
  • Headaches
  • Tiredness and fatigue
  • Feeling dizzy or lightheaded
  • Loss of taste
  • Sensitivity to sunlight
  • Low blood pressure
  • Loss of appetite

Medications that may interact with ACE inhibitors include:

  • Diuretics
  • Other blood pressure medications
  • Medications and supplements containing potassium

Patients who have any of the following medical conditions should speak with a doctor before taking ACE inhibitors:

  • Diabetes
  • Heart disease
  • lupus
  • Hypovolemia
  • Kidney disease
  • Allergies to other medications
  • Aortic valve stenosis

ACE inhibitors may also be unsuitable for patients who have had a heart attack and those who have received a kidney transplant.

Angiotensin II Receptor Blockers

Angiotensin II is an enzyme that narrows the blood vessels. Angiotensin II receptor blockers (ARBs) block the enzyme’s path to specific receptors, which allows the blood vessels to remain open.

Examples of these drugs are:

  • Eprosartan mesylate (Teveten)
  • Irbesartan (Avapro)
  • Valsartan ( Diovan)

Headaches and dizziness are the most common side effects of ARBs. Less common side effects include:

  • Cough
  • Back pain
  • Fever
  • upset stomach
  • Indigestion
  • Joint pain
  • Sore throat
  • Fatigue
  • Nervousness

The following medications can increase or decrease the effect of ARBs:

  • Diuretics
  • Medications and supplements containing potassium
  • Other blood pressure medications
  • Some heart medications
  • Over-the-counter medicines for allergies, colds, and flu

ARBs may not be suitable for people who have previously had a bad reaction to ACE inhibitors. They may also not be suitable for people with the following conditions:

People should not take these drugs during pregnancy.

Calcium Channel Blockers

Calcium causes the smooth muscles of the heart and arteries to contract more strongly.

Calcium channel blockers slow the entry of calcium into these muscles. This reduces the strength of the contractions and lowers the blood pressure.

There are several calcium channel blockers available, such as:

  • Diltiazem hydrochloride (Cardizem)
  • Nifedipine (Procardia XL)
  • Verapamil hydrochloride (Calan SR)

Common side effects of calcium channel blockers include:

  • Tiredness
  • Flushing
  • Swollen feet or ankles

Less common side effects include:

Drinking grapefruit juice while taking some calcium channel blockers can increase the risk of side effects.

Calcium channel blockers may interact with the following medications and supplements:

  • Certain eye medications
  • Diuretics
  • Other blood pressure medications
  • Some heart medications, such as antiarrhythmics and digitalis

People taking more than 60 milligrams per day of some calcium channel blockers may experience low blood sugar levels.

Also, calcium channel blockers may not be suitable for people with the following conditions:

  • Heart failure or other conditions affecting the heart or blood vessels
  • Kidney or liver disease
  • Very low blood pressure

 

Bay Biosciences is a global leader in providing researchers with high-quality, clinical grade, fully characterized human tissue samples, biospecimens, and human biofluid collections.

Samples available include cancer (tumor) tissue, cancer serum, cancer plasma, cancer, peripheral blood mononuclear cells (PBMC). and human tissue samples from various other therapeutic areas and diseases.

In addition, Bay Biosciences maintains and manages its own bio-repository. The human tissue bank (biobank) consisting of thousands of diseased samples (specimens) and from normal healthy donors available in all formats and types.

Moreover, our biobank procures and stores fully consented, de-identified human biospecimens collected under institutional review board (IRB) approved protocols.

Furthermore, all our specimen collections, human tissue samples, and human biofluids are provided with detailed annotations, including associated patients’s clinical data accordingly.

Accordingly, this critical patient’s clinical data includes information relating to their past and current disease, treatment history, lifestyle choices, biomarkers, and genetic information.

Equally important, sample-associated patient’s data is extremely valuable for researchers and is also subsequently used to help identify new effective treatments (drug discovery and development) in oncology and other therapeutic areas and diseases.

Bay Biosciences banks wide variety of human tissue samples and biological samples cryogenically preserved at – 80°C.

In addition, Bay Biosciences has strong capabilities in  collecting and providing human tissue samples according to the researcher’s specified requirements and customized, tailor-made collection protocols.

Please contact us anytime to discuss your special research projects and customized human tissue sample requirements.

Types of Biospecimens

Above all, Bay Biosciences provides human tissue samples (human specimens) from diseased and normal healthy donors which includes:

Notably, we can also procure most human biospecimen types, special sample collections, and requests for human samples that are difficult to find. 

In addition to the standard processing protocols, Bay Biosciences can also provide human plasma, serum, and PBMC bio-fluid samples using custom processing protocols; you buy donor-specific collections in higher volumes and specified sample aliquots from us.

Finally, Bay Biosciences also provides human samples from normal healthy donors; volunteers, for controls and clinical research, contact us Now.

  • 日本のお客様は、ベイバイオサイエンスジャパンBay Biosciences Japanまたはhttp://baybiosciences-jp.com/contact/までご連絡ください。